Sonographic-guided drainage of unilateral hematometrocolpos due to uterus didelphys and obstructed hemivagina associated with ipsilateral renal agenesis.
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Abnormalities, Multiple↗
Biomedical subjects
R M Nowell
Publications and source records attributed to R M Nowell.
Intestinal atony in progressive systemic sclerosis (Scleroderma).
A 27-year-old woman with a long history of scleroderma developed megacolon and severe fecal vomiting as a result of intestinal atony. Evacuation of fecal impaction with water-soluble contrast enema resulted in prompt relief of fecal vomiting and gradual return of bowel function.
Adult↗
Changing ultrasonographic appearance of a vesico-allantoic abdominal wall defect.
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Abdominal Muscles↗
Acetylsalicylate hydrolase of rabbit gastric mucosa. Isolation and purification.
The mechanisn of hydrolysis of acetylsalicylate during absorption from the gastrointestinl tract has been investigated by identification, quantitation, and purification of a hydrolase from gastric mucosal homogenates. The hydrolase was found to be a soluble, cytosolic enzyme with a pH optimum in the slightly alkaline range, pH 8.6 Acetylsalicylate hydrolase activity was purified from the 100,000 g supernatant fraction by differential (NH4)2SO4 fractionation followed by DEAE-cellulose ion-exchange chromatography and Sephadex or Sephacryl gel filtration. The activity could also be fractionated on hydroxylapatite. The Sephadex-purified fraction containing peak enzyme activity gave a single protein band on SDS-polyacrylamide gel electrophoresis. The molecular weight of the acetylsalicylate hydrolase was 66,400 based on SDS-polyacrylamide gel electrophoresis of the Sephadex-purified enzyme and 59,000 based on gel filtration. By use of the technique described, acetylsalicylate hydrolase can be purified over 100-fold to a specific activity of 10.6 mumol . mg-1 . min-1.
Animals↗