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Biomedical subjects

R M Miller

Publications and source records attributed to R M Miller.

At least 91 records · Page 5Linked to original sources
PubMed1980

Head and neck cancer, a rehabilitation approach.

Survival from head and neck cancer is not uncommon. However, treatment is often radical and may compromise the patient's appearance, function, and quality of life. The most common modalities of treatment, employed either singly or in combination, are chemotherapy, radiation, and surgery. Each treatment modality involves unique complications and compromises, many of which are amenable to rehabilitation techniques. A role of the occupational therapist on a cancer rehabilitation team is described and an overview of the therapeutic procedures for the evaluation and treatment of common problems recognized in these patients is presented. The material is derived both from clinical experience of the rehabilitation team and from a literature review employed in developing the rehabilitation program.

Antineoplastic Agents↗
PubMed1979

Skin conductance conditioning with dyshidrotic eczema patients.

Thirty-three patients with dyshidrotic eczema were trained either to decrease or to increase the electrical conductivity of the skin. Skin conductance has been found to be related to epidermal water content as well as emotional variables, both of which have suggested links to eczema. Subjects trained to decrease skin conductance showed clinical improvement more often than the controls who were trained in the opposite direction. They also showed a significant decrease in measured conductance and anxiety. The controls showed increased anxiety and no significant changes in skin conductance level.

Adolescent↗
PubMed1979

Amyotrophic lateral sclerosis: comprehensive management.

The cause of amyotrophic lateral sclerosis remains unknown, and no curative treatment is available. From a rehabilitation perspective, however, comprehensive management and symptomatic treatment can minimize complications, increase function and improve the patient's quality of life. Quinine, diazepam (Valium) and phenytoin (Dilantin) may relieve muscle cramps, and orthoses may permit greater participation in daily activities. Problems with respiration and swallowing may require surgical procedures and the use of feeding tubes. Decisions regarding surgical intervention must be made in the context of the patient's overall status.

Activities of Daily Living↗
PubMed1978

The radiological features of alcoholic ulcero-osteolytic neuropathy in Blacks.

The radiological features in the bones and the angiographic changes in the vessels of the lower limbs of 15 chronic alcoholic men are discussed. The distal arteries demonstrate the features of neovascularization. Infective and resorptive changes in the bones of the forefeet are described. These features are related to chronic infection or to the toxic effects of the alcohol.

Adult↗
PubMed1977

Ultrastructure of elastofibroma.

An elastofibroma from a 69-year-old white man was studied by light and electron microscopy. The lesion was comprised of abundant collagen fibers and numerous randomly disposed masses of amorphous elastinophilic material. Ultrastructurally, this material appeared to be derived from a markedly dense, finely fibrillar precursor secreted by fibroblasts and manifested a striking resemblance to young elastic tissue. Central cores of mature elastic tissue were recognized within some of these elastinophilic masses. This study demonstrates unequivocally that the abnormal elastic material in elastofibroma is derived from excessive production of young elastic tissue and not from elastotic degeneration of collagen, as suggested in some of the previous studies. This young elastic tissue manifests a marked retardation of maturation, the cause of which however is not clear. Another interesting finding in this case was the presence of prominent fibrous laminae within the nuclei of most of the fibroblasts. The significance othis finding is briefly discussed.

Aged↗
PubMed1977

The effects of light and tyrosinase during sclerotium development in Sclerotium rolfsii Sacc.

Some effects of light on morphogenesis in Sclerotium rolfsii Sacc. were studied. Physiological competence to visible light developed during the first 120 h after inoculation, with an optimum sensitivity phase between 84 and 96 h that coincided with the leading hyphae reaching the edge of the Petri dish. Although sclerotial initials were produced in dark-grown cultures, light was necessary for the continuation of the developmental and maturation phases of sclerotial morphogenesis. Tyrosinase activity (o-diphenol: oxygen oxidoreductase, EC 1.10.3.1) was detected during sclerotial formation and the pH and temperature optima for his polyphenol oxidase in vitro were about 6.0 and 45 degrees C respectively. The enzyme was inhibited by cysteine. Similar activity levels of tyrosinase were obtained in blue and "white" light-grown cultures but in red light activity was comparable with that of dark-grown cultures. Laccase activity was not detected at any stage of development.

Catechol Oxidase↗