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Biomedical subjects

R M Mandojana

Publications and source records attributed to R M Mandojana.

9 recordsLinked to original sources

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Hand Dermatoses↗

Recurrent cutaneous jellyfish eruptions without envenomation.

Three patients exhibiting recurrent cutaneous eruptions induced by contact with jellyfish tentacles are presented. The recurrent eruptions appeared several days after the primary exposure without contact with any offending coelenterate. The principal species involved include Pelagia noctiluca, Physalia physalis and probably Lychnorhiza lucerna. These three cases, combined with an earlier similar report of recurrent lesions induced by Physalia physalis suggest that this phenomenon may be widespread. In two of the three cases, the secondary eruption was more severe than that occurring after the primary envenomation.

Adolescent↗

Porokeratosis plantaris discreta.

A 22-year-old black male patient developed discrete, exquisitely painful bilateral plantar lesions. Histologic examination revealed a cutaneous groove filled by a keratin plug (cornoid lamella). There is focal absence of granular layer underlying this defect. The differential diagnosis of this lesion, familiar to podiatrists but relatively unknown to dermatologists, is discussed.

Adult↗

Localized epidermotropic reticulosis (Woringer-Kolopp disease).

In order to clarify the biologic behavior and establish clinical and histologic criteria for the diagnosis of a cutaneous disease originally described by Woringer and Kolopp, we examined fifteen new cases and reviewed thirteen reports. The disease presents as a single, chronic, asymptomatic, circinated, scaly plaque. It preferably involves distal extremities and affects middle-aged individuals, as well as a considerable number of youths. The male to female ratio is 2:1. The treatment of choice is surgical excision or radiotherapy. One lesion resolved with an intralesionally administered steroid. Follow-up data of the twenty-eight cases suggest that this is a benign lesion. Paradoxically, its atypical microscopic features contrast with its benign clinical appearance and biologic behavior. The lower epidermis appears focally infiltrated by large atypical mononuclear cells that spare the dermis. Ultrastructural observations suggest that these are stimulated T lymphocytes, which sometimes are mixed with histiocytes. We propose the term "localized epidermotropic reticulosis" for this distinct clinicopathologic entity, which is different from mycosis fungoides.

Adolescent↗