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Biomedical subjects

R M Lampe

Publications and source records attributed to R M Lampe.

At least 37 records · Page 2Linked to original sources
PubMed1981

The immunoglobulin response to reimmunization with rubella vaccine.

An adolescent military dependent population, 86% of whom had documented history of rubella immunization, was screened by two commercially available rubella hemagglutination inhibition tests. All those who were R-HAI antibody negative were immunized, and postvaccination sera were examined for the development of rubella-specific antibody (R-IgM). R-IgM was not found in any of the previously immunized subjects despite the lack of R-HAI antibody. R-IgM was detected in two seronegative subjects who had no documentation of previous rubella immunization. Thus, although the R-HAI antibody had waned, the engrams of previous immunization remained, resulting in a secondary response on re-exposure. The development of a secondary immune response, despite the absence of detectable r-HAI antibody, casts doubt on the validity of R-HAI as a screening test to determine rubella immunity. The data support continuing mass immunization of preschool children and vaccination of all older females who lack documentation of rubella immunization.

Adolescent↗
PubMed1979

Neonatal scabies.

Scabies contracted during the neonatal period demonstrates a distinct clinical pattern that differs greatly from manifestations seen in older individuals. Involvement of the face, neck, scalp, palms, and soles is a consistent finding, as is the tendency for these lesions to form pustules early in the course of the infestation. Poor feeding and failure to gain weight appropriately are also characteristic features. The skin lesions include erythematous papules, nodular crusts, and putules. The possibility of scabies should be entertained for any young infant who has these findings. Scrapings should be obtained from multiple sites to confirm the diagnosis. In the absence of positive findings for scrapings, examination of close contacts and a careful history should lead to the correct diagnosis.

Female↗
PubMed1979

Jimson "loco" weed abuse in adolescents.

Over a three-year period, 29 adolescent patients were hospitalized because of intentional Jimson weed ingestion. Their records were reviewed for the presence of signs and symptoms of atropine/scopolamine toxicity clinical course, treatment, and outcome. Twenty-two were male and seven were female. All had mydriasis, hallucinations, and were disoriented. Tachycardia (heart rate greater than 95), dry mucous membranes, and flushed facies were often present. Urinary retention requiring catheterization was present in five patients. Sixty-five percent (17/26) had detectable atropine or scopolamine in their urine. The average length of hospitalization was 1.8 days. No serious complications were encountered during hospitalization and full recovery were noted in all patients. Gastric lavage and hospital admission for close monitoring and medical support are essential phases of management. Physicians who care for adolescents should be aware of this relatively new form of drug abuse and its management.

Adolescent↗
PubMed1977

Sequential treatment with quinine and mefloquine or quinine and pyrimethamine-sulfadoxine for falciparum malaria.

Patients with falciparum malaria were studied in Thailand, an area of known chloroquine resistance. The patients were unselected and some had severe malaria, and they were randomly assigned to one of two sequential regimes. A short course of quinine (average 4 doses, equivalent to 2 g base) followed by a single dose of pyrimethamine-sulfadoxine (Fansidar) cured 92% of patients (36 out of 39), while a short course of quinine followed by a single 1-5-dose of mefloquine cured all of the 35 patients who could be followed up. Gastrointestinal side effects were minimal if at least 12 hours elapsed between the last dose of quinine and the mefloquine. Sequential quinine and mefloquine is the most effective treatment for patients with chloroquine-resistant falciparum malaria, including those with severe or complicated disease. Mefloquine, however, is not commercially available, and the similar regimen using Fansidar is almost as effective.

Adolescent↗
PubMed1977

Green hair.

Explore the source record for details and available documents.

Child↗
PubMed1976

Detection of bacterial antigen in pleural fluid by counterimmunoelectrophoresis.

Pleural fluid specimens from 87 patients were studied using counterimmunoelectrophoresis with pneumococcal, staphylococcal, and Hemophilus influenza b antisera. This method compared favorably with traditional bacteriologic methods and in addition provided a presumptive etiologic diagnosis in more than half of the specimens with negative bacterial cultures. One cross-reaction between H. influenza b antiserum and a pleural fluid specimen with an Escherichia coli isolate was observed.

Antigens, Bacterial↗