Biomedical subjects

R M King

Publications and source records attributed to R M King.

57 records · Page 4Linked to original sources

PubMedDate not supplied

Comparison of staples and sutures for cardiorrhaphy in traumatic puncture wounds of the heart.

The purpose of this study was to compare the traditional method for repair of cardiac lacerations using sutures and pledgets (S/P) with repair using a skin stapling device (SSD) performed by emergency medicine residents. In a prospective, randomized, non-blinded animal study, 20 anesthetized mongrel dogs were instrumented and underwent left lateral thoracotomy, pericardiotomy, and cardiac exposure. In set 1, a standardized 8-mm right ventricular stab wound was made with a #10 scalpel; emergency medicine residents then immediately performed emergent cardiorrhaphy by either S/P (n = 5) or SSD (n = 5) technique. In set 2, 10 dogs received standardized 8-mm right ventricular stab wounds followed by repair and then received a second stab wound to the same right ventricle that was subsequently repaired by the same operator using the alternate technique. All dogs were observed for 60 min for gross blood loss, hemodynamic instability, and integrity of repair. The results demonstrate that SSD cardiorrhaphy was significantly faster (29 +/- 11 sec in set 1; 14 +/- 6 sec in set 2) than S/P repair (201 +/- 10 sec in set 1; 196 +/- 59 sec in set 2). No appreciable differences in blood loss or repair integrity were noted in either group. Two operators in the S/P group suffered needle puncture injuries. In conclusion, cardiorrhaphy by SSD is faster to perform, has similar repair integrity, and has less risk of accidental contaminated needle injury than does traditional S/P repair when performed by emergency medicine residents.

Animals↗

PubMedDate not supplied

Experience with the Sarns centrifugal pump as a ventricular assist device.

The authors used the Sarns centrifugal pump (Sarns 3M, Ann Arbor, MI) as a ventricular assist device (VAD) in 30 patients between May 1985 and February 1990. Sixteen patients were unweanable from cardiopulmonary bypass at the time of surgery; nine were patients who developed cardiogenic shock postoperatively in the intensive care unit. One was a donor organ failure; one had a failed PTCA; and one an acute myocardial infarction with cardiogenic shock preoperatively. Two patients were bridged to cardiac transplantation. Of the 28 nontransplant candidates, 20 (71.4%) were weaned successfully, 14 (50%) were discharged from the hospital, and 13 (46%) are alive from 1 to 46 months postoperatively (mean, 21.1 months). Three patients received right ventricular support alone; all three were weaned, and two (66.7%) were discharged. Ten patients received left ventricular assistance alone. Six (60%) were weaned, and four (40%) were discharged. Two patients received left ventricular support initially but were taken back for right VAD insertion because of right-sided heart failure; one (50%) is alive. Fifteen patients received biventricular support. Eleven (77.3%) were weaned, and eight (53.3%) were discharged. Patient ages ranged from 19 to 73 years, with a mean age for men of 59 years and 50.5 years for women. There were no thromboembolic events. Various clinical parameters were evaluated to determine effect on weanability and survival. These results show survival equivalent to any other VAD at this time. The centrifugal pump is a convenient and effective means of maintaining ventricular support in individuals who are believed to have salvageable myocardium.

Cardiopulmonary Bypass↗

PubMedDate not supplied

Renal artery graft-to-duodenum fistula: unusual presentation of a recurrent flank abscess.

Perhaps the most devastating complication of a prosthetic vascular graft is the formation of an aortoenteric fistula. Most reports have dealt with fistulas between the aortic graft and the duodenum, although any revascularized vessel with prosthetic material can be the site of an enteric fistula. We report an unusual case in which a renal artery previously revascularized with a silk prosthetic graft developed a fistula to the duodenum 16 years later. Whether the prosthetic graft is in the aortic position or to a visceral vessel, when a fistula develops the only acceptable treatment is complete removal of the graft and revascularization with autogenous tissues, if necessary.

Adult↗