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Biomedical subjects

R M Higgins

Publications and source records attributed to R M Higgins.

58 records · Page 4Linked to original sources
PubMedDate not supplied

Replantation of digits.

Replantation surgery has come of age in the past 20 years. Sophisticated microsurgical techniques, improved preservation methods, and increased understanding of ischemia time have all contributed to the growth of digital replantation as a viable surgical process. The complexity of the surgeries warrants a review of nursing management, pharmacologic modalities, and monitoring alternatives. This article explores rehabilitative therapies in relation to successful patient outcomes.

Amputation, Traumatic↗
PubMedDate not supplied

Changes in blood gas levels after nebuhaler and nebulizer administration of terbutaline in severe chronic airway obstruction.

It has been suggested that patients with severe chronic airway obstruction might suffer dangerous hypoxia after administration of a beta-agonist through an air driven nebulizer. Twenty patients with severe chronic airway obstruction (12 male, mean age 71.1 (SEM 1.5) yr) were monitored with a Biox oximeter and Hewlett-Packard capnometer before and after 4 mg terbutaline was delivered through an air driven nebulizer or Nebuhaler. The eight patients with chronic hypoxia (mean PaO2 6.76 kPa, PaCO2 7.47 kPa. FEV1 0.53 l) experienced a 4.7% increase in oxygen saturation (SaO2) and 2.9% fall in transcutaneous carbon dioxide tension (PtcCO2) (p less than 0.05) during all treatments, followed by a return to initial levels. These changes were attributable to increased ventilation whilst breathing through a mouthpiece. A similar trend was seen in the SaO2 of the twelve normoxic patients (mean PaO2 9.32 kPa, PaCO2 5.34 kPa, FEV1 0.8 l), but there was a sustained fall in PtcCO2 of 3.7% (p less than 0.001) after administration of terbutaline. Inhaled terbutaline in the dosage given did not cause hypoxia in patients with severe chronic airflow obstruction, but nebulizer and Nebuhaler use was associated with a rise in SaO2 related to increased ventilation whilst breathing through a mouthpiece.

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