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Biomedical subjects

R M Gore

Publications and source records attributed to R M Gore.

At least 73 records · Page 4Linked to original sources

CT findings in ulcerative, granulomatous, and indeterminate colitis.

Eight patients with ulcerative colitis, three with colitis indeterminate, and 15 patients with Crohn disease were studied by computed tomography (CT) to establish CT criteria for each disorder in hopes of providing a new diagnostic perspective useful in the radiographic evaluation of inflammatory colitis. The CT findings in ulcerative colitis included thickening of the colon wall (mean, 7.8 mm), which was characterized by inhomogeneous attenuation and a "target" appearance of the rectum, and proliferation of perirectal fat. Bowel wall thickening (mean, 13 mm) with homogeneous attenuation, fistula and abscess formation, and mesenteric abnormalities were observed in patients with Crohn colitis. Patients with colitis indeterminate showed colonic changes on CT observed in both disorders. Initial experience suggests that CT can differentiate patients with well established ulcerative and Crohn colitis.

Abscess↗

Value of computed tomography in interstitial 125I brachytherapy of prostatic carcinoma.

Computed tomography (CT) was performed in 20 patients with localized prostatic carcinoma before and after interstitial implantation of 125I seeds. Scans were analyzed to determine prostate volume, seed location, tumor response, and periprostatic tumor spread. CT volumes were an average of 25-30% greater than clinical estimates. In addition, CT demonstrated errors in implantation, including inhomogeneous distribution and extraprostatic seeds, in 17 patients (85%). Serial post-implantation scans showed no change in prostate volume in 12 patients (60%), a decrease in 7 (35%), and an increase in 1 (5%), concurring with clinical assessment of response to therapy. In 2 patients, clinically unsuspected tumor spread was identified on the CT scan.

Aged↗

Ultrasonic evaluation of common bile duct stones: prospective comparison with endoscopic retrograde cholangiopancreatography.

Ultrasound is the modality of choice for the diagnosis of cholelithiasis and for the evaluation of the intra- and extrahepatic biliary tree in the patient with jaundice, but its role in the diagnosis of choledocholithiasis is less certain. We prospectively examined 90 patients who were to undergo endoscopic retrograde cholangiopancreatography (ERCP) by performing right upper quadrant sonography immediately prior to ERCP. We assessed the size of the intra- and extrahepatic ducts and the presence or absence of calculi. ERCP, which was successfully performed in 77 of 94 attempted examinations, percutaneous transhepatic cholangiography, or surgical follow-up composed the diagnostic standard for comparison. Ultrasound was not accurate in the diagnosis (sensitivity, 25%) or exclusion (value of a negative study, 73%) of choledocholithiasis. Furthermore, in the postcholecystectomy patient population, ultrasound assessment of biliary duct size is not a useful predictor of biliary disease. For symptomatic postcholecystectomy patients, we recommend ERCP as the initial diagnostic modality.

Bile Duct Diseases↗

Computed tomography in the evaluation of Crohn disease.

The abdominal and pelvic computed tomographic examinations in 28 patients with Crohn disease were analyzed and correlated with conventional barium studies, sinograms, and surgical findings. Mucosal abnormalities such as aphthous lesions, pseudopolyps, and ulcerations were only imaged by conventional techniques. Computed tomography proved superior in demonstrating the mural, serosal, and mesenteric abnormalities such as bowel wall thickening (82%), fibrofatty proliferation of mesenteric fat (39%), mesenteric abscess (25%), inflammatory reaction of the mesentery (14%), and mesenteric lymphadenopathy (18%). Computed tomography was most useful clinically in defining the nature of mass effects, separation, or displacement of small bowel segments seen on small bowel series. Although conventional barium studies remain the initial diagnostic procedure in evaluating Crohn disease, computed tomography can be a useful adjunct in resolving difficult clinical and radiologic diagnostic problems.

Abscess↗

Hepatic portal venous gas: a benign finding in a patient with ulcerative colitis.

Hepatic portal vein gas (HPVG) usually occurs in conjunction with an abdominal catastrophe such as bowel infarction or necrotizing enterocolitis. We describe this finding after air contrast barium enema in a patient with stable chronic ulcerative colitis who had no symptoms, morbidity, or sequelae, and discuss the diagnostic and therapeutic implications of HPVG.

Adult↗

Esophageal manifestations of Crohn's disease.

Two patients with concurrent esophagitis and ileocolitis due to Crohn's disease are presented. The initial feature of esophageal involvement was dysphagia caused by severe inflammation of the distal esophagus with mucosal ulcerations and polypoid folds. Long-term observation of both cases revealed a gradually progressive course leading to development of rigid esophageal structure, intramural sinus tract, and esophagobronchial or esophagogastric fistulas. The clinical and radiographic manifestations of Crohn's esophagitis in these 2 patients and in 18 previously reported cases are reviewed.

Adult↗

Displaced retroperitoneal fat: sonographic guide to right upper quadrant mass localization.

While it is often easy to detect masses in the right upper quadrant that originate from the liver, adrenal gland, or kidney, it may be difficult to determine the anatomic origin of large masses in the posterior aspect of the right upper quadrant. In this paper it is reported that the reflection produced by right upper quadrant retroperitoneal fat is displaced in a characteristic manner by masses originating in this area. This greatly assists in the localization of these masses. Hepatic and subhepatic masses posteriorly displace this echo, while renal and adrenal lesions anteriorly displace it.

Abdominal Neoplasms↗

Abdominal manifestations of pediatric leukemias: sonographic assessment.

The abdominal sonograms of 64 leukemic children were reviewed and correlated with clinical, hematological, and, when available, autopsy findings. Sonographic abnormalities including enlargement of the liver, spleen, pancreas, and kidneys, with or without alteration of parenchymal echo architecture, hydronephrosis, lymphadenopathy, and ascites were encountered in 70% of the patients. Ultrasound proved useful in detecting occult visceral leukemia and relapse, monitoring tumor response to chemotherapy, and assessing the complications of chemotherapy. Ultrasound is recommended for the routine evaluation and follow-up of the pediatric leukemic patient.

Abdominal Neoplasms↗