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Biomedical subjects

R M Aspden

Publications and source records attributed to R M Aspden.

74 records · Page 5Linked to original sources

Determination of collagen fibril orientation in the cartilage of vertebral end plate.

X-Ray diffraction and scanning electron microscopy show that collagen fibrils tend to be oriented parallel to the surface of the vertebral end plates in pig, rat and man. It is suggested that this orientation allows the end plate to withstand the pressure exerted on it by the nucleus pulposus. Scanning electron microscopy shows that lamellae occur in human end plates. Collagen fibrils also tend to be preferentially aligned in the direction of the ventral-dorsal axis.

Adolescent↗

The lamina splendens of articular cartilage is an artefact of phase contrast microscopy.

The so-called lamina splendens of articular cartilage is shown to be a characteristic of phase contrast microscopy; this technique provides no evidence for an anatomically distinct surface layer. Fresnel diffraction occurs at edges separating regions of different refractive indices. These diffraction effects, when viewed under phase contrast, lead to the appearance of a bright line along the edge.

Adolescent↗