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Biomedical subjects

R Lohrmann

Publications and source records attributed to R Lohrmann.

48 records · Page 3Linked to original sources
PubMed1968

Partial resolution of DL-adenosine by template synthesis.

D-Adenosine-5'-phosphorimidazolide reacts very much more rapidly with D-adenosine than with L-adenosine on a poly-D-uridylic acid template. This permits the partial resolution of DL-adenosine. These experiments suggest that segregation of D- and L-nucleotides may have occurred at an early stage in biochemical evolution.

Adenine Nucleotides↗
PubMed1968

Prebiotic synthesis: phosphorylation in aqueous solution.

Formation of uridine-5'-phosphate from uridine and inorganic phosphate in aqueous solution is effected by the following condensing agents: cyanogen, cyanoformamide, cyanate, cyanamide, thioformate, ethylisocyanide, and a watersoluble carbodiimide. The yields are always small, even when a large excess of condensing agent is used. The cyclization of uridine-3'-(2')-phosphate occurs under the same conditions but in much greater yield.

Amides↗
PubMed1967

Phosphorylation with inorganic phosphates at moderate temperatures.

Uridine phosphates may be obtained by heating uridine with inorganic phosphates for 9 months at temperatures as low as 65 degrees C. Under similar conditions, uridine-5'-phosphate, in addition to forming uridine diphosphates, undergoes some dephosphorylation to give uridine.

Hot Temperature↗