[Current aspects of coronary surgery].
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Biomedical subjects
Publications and source records attributed to R Limet.
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Vein grafts to left-sided coronary arteries, unlike those to the right coronary artery, do not course and land naturally on an axis parallel to that of the recipient artery. To run such a course, the graft must take off from the aorta in a direction upward and to the left, then loop back toward the left anterior descending, the diagonal, or the circumflex coronary artery. Because of limited space in this area due to the reflection of the pericardium near the left pulmonary artery and left atrial appendage, the vein loop may bend at that point or, when made shorter, may kink at the site of the coronary anastomosis. To avoid the formation of these sharp angulations, the graft may be made to course posteriorly and superiorly into the transverse sinus, behind the main pulmonary artery and the aorta, and may be sutured on the right anterior aspect of the ascending aorta. Following is the description of this technique and its advantages.
In a series of 7 dogs, selective stimulation of the carotid body receptors by hypoxic blood produces an increase of coronary flow and greater release of norepinephrine from the heart; the increase of coronary flow is less marked and the release of norepinephrine is increased after vagotomy. Myocardial norepinephrine content is decreased by carotid body stimulation.
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It is of great importance to perform the most complete possible correction of multiple coronoronary vessels was shown at the Institut de Cardiologie de Montreal: early occlucion of grafts was low (1/32) and early occlusion of one of the anastomoses was acceptable (5/32). At one year follow-up (20 of the 32 grafts reviewed early), no additional total graft thrombosis was noted and only 2 more end-anastomes were lost. These rates of thrombosis are lover than those generally reported for series with a single anastomosis. The diagonal and anterior interventricular branches yield well to this technique; the main deterrent is the occurrence of unfavorable kinking of the graft.
In a series of 11 dogs, selective stimulation of the carotid body receptors by hypoxic, hypercapnic, acidotic blood produces bradycardia, an increase of coronary flow, and greater release of norepinephrine from the heart; the coronary resistances are decreased. The same stimulation after vagotomy is no longer accompanied by bradycardia; the decrease of coronary resistance is less marked and the release of norephinephrine is increased.
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Use of the intra-aortic balloon in the treatment of circulatory failure after cardiac surgery has resulted in the long-term survival of 7 patients out of 20. The failures occured when the myocardium is severely compromised so that any treatment is likely to fait (8/13), and where there is the ultimate complication of renal or hepatic failure (4/13), irreversible ventricular failure or secondary haemorrhage. In urgent coronary bypass surgery (4/13) it would appear that the use of the balloon preoperatively would have avoided or at least slowed the progress toward the anatomical changes of massive infarction. As the use of the balloon has often been associated with a reduction in the number of circulating platelets and a pathological increase in the breakdow products of fibrin, heparin is now used systematically in an attempt to prevent the development of a true intravascular coagulation syndrome. The use of lidocaine is also recommended to prevent fatal or dangerous ventricular arrhythmias when the balloon is functioning well. A combination of the intra-aortic balloon with the infusion of small doses of adrenaline would seem to be an interesting therapeutic combination, especially at the onset of counterpressure.
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A study evaluating the durability of two recent techniques of tricuspid annuloplasty was conducted simultaneously in two institutions. One group working in Madrid, Spain, used Carpentier's ring in 32 patients. The other in Montreal, Canada, employed De Vega's semicircular annuloplasty in 17 cases. Competence of the tricuspid valve was obtained in nearly all cases at the time of surgery and persisted after a mean follow-up of 10.3 months (Madrid) and 11.5 months (Montreal) in 77 per cent of the cases. Light (1/3) residual tricuspid insufficiency was detected in 16.5 per cent; moderate (2/3) incompetence persisted in only 6.5 per cent. The majority of the patients with residual tricuspid insufficiency had unsuccessful or incomplete repair of left-sided heart lesions.
A computer simulation of the left coronary outflow response to branch occlusion was carried out, using physiological data derived from canine left coronary artery generated on an IBM 360/44 in order to provide multidimensional analysis of the problem of the distribution of flow within the myocardium. During coronary occlusion in this computer model, distal impedance varied little during the occlusion of one or the other arterial brance. This observation was taken as a boundary condition in the simulation exercise. Some of the important factors in the intramyocardial distribution of flow are discussed.
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