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Biomedical subjects

R Lampugnani

Publications and source records attributed to R Lampugnani.

32 records · Page 2Linked to original sources
PubMed1980

Response of pathological ischaemic muscle pain to analgesics.

1 Twenty-four patients suffering from severe pain due to chronic occlusive arterial disease of the legs were given oral doses of indoprofen (200 mg), ibuprofen (300 mg) and placebo. 2 Differences in pain intensity scored on a five-point scale were taken as measurement of pain relief. 3 This double-blind, cross-over trial showed that indoprofen had significantly greater analgesic effect than placebo and reference drug. 4 From a methodological point of view there are many arguments on favour of pathological ischaemic pain as a test for clinical assessment of analgesics.

Aged↗
PubMed1979

[Experimental acute pancreatitis caused by papillary lesions in the rat].

The importance of the papillary structure in the control of biliary and pancreatic outflow induced the authors to investigate the effect of papillary damage, chemical and physical, on the pancreatic parenchyma of the rat. The results show that mild papillary lesions produce acute interstitial flogosis of the pancreas; in 16,6% of the investigated animals this inflammation develops with the clear findings of a lethal acute haemorrhagic pancreatitis. This model is like the aspects of the post-operative acute pancreatitis.

Acute Disease↗
PubMed1979

[Parathyroidectomy for secondary hyperparathyroidism: anatomo-surgical observations on experience in 16 treated cases].

The authors, on personal experience, based on parathyroidectomies for secondary hyperparathyroidism, relate the surgical anatomic findings after a brief discussion on indications. They relate beside some atypical seats of parathyroid glands, observed in 11 glands of the 59 removed. Finally they emphasize the importance of accuracy of surgical exploration because that cannot be helped by instrumental methods or by gross pathologic observation.

Adult↗
PubMed1979

[Comparison between lymphangiovenous and adeno-lymphovenous anastomoses in the rat with mesenteric lymphostasis].

A comparison between lymphangiovenous and lymphadeno-venous anastomoses has been realized in rats with mesenteric lymphostasis. The lymphangiovenous anastomoses have showed a better patency than lymphonode-venous shunt owing to technics and biologic problems. Their function was verified until 15th p.o. day, while all lymphonode venous shunt were closed at 10 th p.o.. The shunt occlusion may be related with lymphatic newborn vessels, which exclude the anastomoses from lymph flow.

Animals↗
PubMed1979

[Vascular and histological changes in rat liver after porta-systemic shunt].

The authors analyze vascular liver modifications after porta-caval shunt in the rat. The examination of the portal vascular bed obtained by neoprene latex injection allows the definition of different morphologic phases, throughout these liver reaches new structural balance, with an efficacious lobular perfusion. In the same periods histological findings show a cell damage, without necrosis, followed by a recovery after 8 months. In distance, in normal rat porta-caval shunts induce a reduction of the liver volume, both the lobular structures have normal functions and morphology.

Animals↗
PubMed1975

[Chromosomal diseases of surgical interest].

After a short review of the most common chromosomic diseases, the possibility of surgical action in some of these "chromosomic patients" is suggested. This possibility would appear to arise from a careful analysis involving various health components. In conclusion some working hypotheses which might be developed in the by no means distant future are discussed.

Chromosome Aberrations↗
PubMedDate not supplied

[Secondary hyperparathyroidism].

We reviewed the results of twenty-four years' experience of parathyroidectomy for secondary hyperparathyroidism. Over the period from 1976 to 2000, we performed 171 parathyroidectomies for secondary hyperparathyroidism (91 males, 80 females; median age: 57.4). Autotransplantation was performed in 45. Of the 171 patients undergoing parathyroidectomy, 14 (8.1%) were treated for relapse. Twenty-four of the 45 patients treated with autotransplantation (53.3%) were followed up for 82 +/- 37 months. Hypoparathyroidism was observed in 33.3% of these (worse after 6 months in 21% and stable in 46%). Five patients (11.1%) experienced a relapse of hyperparathyroidism. We believe that the treatment of choice for secondary hyperparathyroidism is subtotal parathyroidectomy, the indications for autotransplantation in parathyroid surgery are rare.

Female↗