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Biomedical subjects

R Labrecque

Publications and source records attributed to R Labrecque.

27 records · Page 2Linked to original sources
PubMed1979

[Binswanger's subcortical encephalopathy. Study of a case with predominant left hemispheric lesion (author's transl)].

We report the clinical and pathological study of a patient with vascular leucoencephalopathy almost restricted to the left posterior hemisphere. A 65 year--old right handed hypertensive woman has presented with a neuropsychological symptomatology of transcortical sensorial aphasia. We discuss the following points: 1) the patient's disease must be considered as Binswanger's subcortical encephalopathy despite the asymetric topography of the lesions ; 2) particular hemodynamic cerebral factors has possibly determined the asymetric nature of the disease ; 3) a lesion of the left temporo-parieto-occipital area that was strictly sub-cortical, with complete destruction of the posterior part of the arcuate fasciculus has presented with the clinical picture of a transcortical sensorial aphasia.

Aged↗
PubMed1977

Action of FdUrD and dCyd on the incorporation of BrdUrd in chinese hamster somatic cell DNA and the isolation of auxotrophic mutants.

Chinese hamster somatic cells grown in the presence of bromodeoxyuridine, deoxycytidine and fluorodeoxyuridine incorporate more bromodeoxyuridine in the DNA than cells grown in the presence of bromodeoxyuridine alone. Thus they become more sensitive to light irradiation. Our data suggest that 0.05 mM--0.2 mM bromodeoxyuridine, 0.05 mM deoxyctidine and 10 mmug/ml fluorodeoxyuridine is one of the best possible combinations for the selection of Chinese hamster somatic cells mutants. Auxotrophs for proline, inositol or both were thus isolated at high frequency.

Animals↗
PubMedDate not supplied

[Progressive multifocal leukoencephalopathy and hemochromatosis. Pathological study of a case (author's transl)].

A case of progressive multifocal leukoencephalopathy (P.M.L.) with humoral immunologic deficiency and hemochromatosis has been studied by light and electron microscopy. Widespread demyelination of white substance, gigantic astrocytes, inflammatory perivascular cuffs and numerous nuclear and cytoplasmic viral inclusions, suggesting Papovavirus were observed. The relationship between P.M.L. and hemochromatosis is discussed.

Adult↗
PubMedDate not supplied

[Capsulo-thalamic hemorrhage (author's transl)].

The authors report clinical and scanographic findings in 26 cases of capsulo-thalamic hemorrhage. They stress the frequency of arterial hypertension as a pre-disposing factor. The clinical picture is represented by the association of disorders of consciousness (usually obnubilation), contralateral flaccid hemiplegia with hemianesthesia, oculomotor disorders (disturbance of vertical gaze, miosis) and disorders of linguistic and motor behaviour. The paraclinical examination of choice is scanography which enables the site, volume and extent of the hemorrhage to be estimated, together with the mass effect and intraventricular rupture. Clinical and scanographic follow-up indicates a favourable prognosis for capsulo-thalamic hemorrhage (77% survival). Follow-up findings point to several unfavourable prognostic factors: immediate coma, persistent and massive flaccid hemiplegia, hemorrhage size exceeding 3 cm, and severe intraventricular rupture. In the light of the data in the literature, the authors discuss the clinical and scanographic signs of capsulo-thalamic hemorrhage.

Aged↗