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Biomedical subjects

R L Levy

Publications and source records attributed to R L Levy.

13 recordsLinked to original sources
PubMed1979

The relationship of an overt commitment to the frequency and speed of compliance with symptom reporting.

This study investigates the effect of an overt verbal commitment on compliance with returning symptom report cards. Patients in two flu inoculation clinics were placed in an experimental condition. Patients in two other comparable flu inoculation clinics were placed in the control condition. After receiving their inoculations, all patients were asked to mail back a postcard after 48 hours that indicated the occurance of any symptoms. Patients in the experimental condition were asked if they would comply with the request. Patients in the control condition were not asked for a commitment. Patients in the experimental condition returned significantly more cards and significantly sooner than those in the control condition. This technique has both clinical and research applications.

Behavior Therapy↗
PubMed1979

Social work and dentistry in clinical, training and research collaboration.

The knowledge and knowledge building skills of social workers can improve in three ways the quality and type of services provided to dental patients. First, social workers can be involved in the training of dental professionals so as to improve their interactions with patients. Second, social workers may provide social work clinical services to dental patients. Finally, social workers can conduct research that can add to the body of knowledge on patient behaviors relevant to dental treatment. This paper outlines a program conducted by social workers that incorporates all three of these activities.

Dentistry↗
PubMed1978

Quantitation of antibodies to IgM, IgD and beta2-microglobulin in antisera to chronic lymphatic leukemia lymphocytes.

Rabbit antisera were prepared to chronic lymphatic leukemia (CLL) lymphocytes and were tested for their reaction with radioiodinated, solubilized, cell surface proteins of normal and CLL lymphocytes. A pooled, hyperimmune antiserum precipitated at least 16 polypeptides from both normal and CLL lymphocytes as shown by sodium-dodecyl sulfate polyacrylamide gel electrophoresis. These polypeptides varied in molecular weight from 11,000 to 180,000. None was prominent or unique to the CLL lymphocytes, although four peptide bands in the CLL cells usually showed more radioactivity than their counterparts in normal cells. Precipitation with antisera of known specificity showed that the cell surface proteins from CLL and normal lymphocytes included HLA antigens and beta2-microglobulin. IgM and IgD were found in preparations of normal cells and in cells of 3 of 5 CLL patients. Of cells from the other 2 patients, one showed only IgD and the other no Ig. An antigen-binding capacity test was employed to quantitate the antibody content of a pooled anti-CLL lymphocyte serum. The antiserum reacted with all Ig classes; however, after absorption with light chains and F(ab')2 fragments, the serum retained activity only for IgM and IgD. The absorbed antiserum bound 45 microgram IgM, 1.5 microgram IgD and 4.5 microgram beta2-microglobulin per milliliter. These data indicate that rabbit anti-CLL lymphocyte sera fail to detect a qualitatively unique tumor-specific polypeptide on the surfaces of CLL cells. However, such antisera contain antibodies to many cell surface proteins including IgM, IgD, HLA antigens and beta2-microglobulin.

Antibodies↗
PubMed1977

Immunosuppressive effects of 3-methylcholanthrene given intratracheally in various inbred strains of mice.

The immunosuppressive effects of 3-methylcholanthrene (MCA) given intratracheally have been shown to correlate with susceptibility of some inbred strains of mice to MCA-induced carcinogenesis. In susceptible strains of mice, C3Hf and C57BL/6, intratracheal administration of MCA resulted in profound systemic immunodepression. This effect was not observed in resistant DBA/2 mice. This immunodepressive effect correlated with the inducibility of the aryl hydrocarbon hydroxylase enzyme complex and the inducibility of pulmonary tumors by MCA.

Animals↗
PubMed1976

Behavior therapy techniques as a fulfillment of community mental health ideology.

Due to value orientations, lack of knowledge, or exposure, the behavioral approach has been avoided by many professionals in the community mental health field. This is unfortunate, because many concepts of behavior analysis are identical to some of the guiding principles of the community mental health movement. Furthermore, the methods derived from a behavioral framework can help implement the community mental health idiology. This paper identifies possible linkages in the areas of treatment, client population, and evaluation.

Behavior Therapy↗
PubMed1976

Enhancement of infectivity and oncogenicity of a murine leukemia virus in adult mice by X-irradiation.

Infection of adult BALB/c mice with murine leukemia virus (MuLV) induces thymic lymphomas histologically indistinguishable from those caused by neonatal infection. X-irradiation permitted early and high levels of viral expression when given before or after MuLV administration and hastened the development of lymphomas. Expression of virus was assayed by using a radioimmune assay for murine p30, a virion core protein. Seventeen to 21 days after injection of MuLV into adult mice, there was 0.3 mug p30 per ml serum, approximately 5 times normal. Seventeen to 21 days after injection of MuLV into X-irradiated (600R) adult mice, there were 2.7 mug p30 per ml serum. The virus produced by infected adult mice was infectious and oncogenic when given to newborn mice.

Age Factors↗
PubMed1975

Biochemical and immunologic characterization of an oncornavirus glycoprotein.

Studies were carried out on an oncogenic C-type virus, Scripps leukemia virus (SLV), produced by a lymphoblastoid cell line (SCRF 60A) from a New Zealand Black (NZB) mouse. A 70,000 dalton glycoprotein on the virion surface constitutes about 10% of the virion amino acids and about 50% of the glucosamine. The protein can be isolated from surface iodinated SCRF 60A cells as well as from a line of nonproducer cells. This protein reacts with sera which neutralize Moloney, Kirsten, Rauscher, AKR, and, of course, Scripps viruses. These data suggest that this is the principal antigen detected by immunofluorescence on the surface of cells infected with murine leukemia virus (MuLV) and that this antigen may be involved in virus neutralization.

Amino Acids↗