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Biomedical subjects

R L Jetton

Publications and source records attributed to R L Jetton.

15 recordsLinked to original sources

Sclerosing panniculitis. A clinicopathologic assessment.

Six patients with well-circumscribed, indurated, inflammatory plaques of the lower extremity are described. Incisional biopsy specimens in each patient revealed fat necrosis, sclerosis, and a lobular panniculitis. These patients are similar to those described under the designations hypodermitis sclerodermaformis or lipodermatosclerosis. The name sclerosing panniculitis is proposed to unify these conditions. The pathogenesis is unknown, although a role for venous stasis or previous thrombophlebitis has been proposed. Systemic or local anti-inflammatory therapies have not been clinically effective.

Adult↗

Minidose heparin therapy for vasculitis of atrophie blanche.

Atrophie blanche vasculitis is due to thromboocclusion of dermal blood vessels. A 28-year-old white man with a very severe case of this disease had a complete remission when he was treated with minidose heparin sodium injections. As little as 5,000 U of heparin every 3 days controlled his vasculitis. Further reduction of heparin dose resulted in an exacerbation of disease which was controlled with more vigorous heparin therapy. The role of minidose heparin in cutaneous disease is discussed.

Adult↗