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Biomedical subjects

R L Gregory

Publications and source records attributed to R L Gregory.

18 recordsLinked to original sources

Stereo vision and isoluminance.

Recent experiments have shown that stereo depth is given by fusion of illusory ('cognitive') contours. They occur across quite large gaps in figures, when these gaps are unlikely and form the shape of a probable (nearer) masking object or masking feature. Implications are that: (a) clearly defined contours and regions of brightness difference can be produced as postulates from sensory evidence, which may be surprising absence of stimulation; (b) each eye-system can derive its own postulates, or hypotheses, which (c) can be combined to give stereo vision. It has been shown that random-dot stereo depth does not occur when there is colour contrast but no brightness difference between the dots and their background. This we have confirmed by using a new technique for producing isoluminant pictures, of any complexity, with exact registration for any two colours. With this technique, we find large displacements of narrow borders bounding regions that are shifted across isoluminance. These displacements, which are clearly seen as movements, occur with or without colour differences. The direction of shift depends on whether the narrow border is light or dark. It is found that these dramatic shifts do not - when produced in opposite directions to the two eyes and fused - produce stereo depth. It is concluded, following Julesz's paradigm, that these contour displacements have their neural orgin not retinally, but after stereo fusion. Experiments combining the 'cognitive contours' stereo depth with isoluminance are described.

Color

What a joke.

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England

Border locking and the Café Wall illusion.

The Café Wall illusion (seen on the tiles of a local café) is a Münsterberg chequerboard figure, but with horizontal parallel lines which may have any luminance separating the rows of displaced squares. These (the 'mortar' lines) display marked wedge distortion which is especially affected by: contrast of the squares ('tiles'); width of the 'mortar' lines, and their luminance which must not be significantly higher than that of the light squares or lower than that of the dark squares for distortion to occur. An experiment is described from which quantitative data have been obtained by varying these parameters. It is suggested that contiguous regions of different luminance (and contiguous colour regions) are normally held in spatial register by locking from common luminance boundaries. The Café Wall illusion is attributed to this border locking producing inappropriate contour shifts from neighbouring regions of contrasting luminance when separated by narrow gaps of neutral luminance. Further implications on the border-locking notion are discussed.

Discrimination Learning

Speech recognition with dynamic range reduction: (1) deaf and normal subjects in laboratory conditions.

Processing to reduce the dynamic range of speech should increase intelligibility and protect the impaired ear from overloading. There are theoretical and practical objections to using AGC devices to reduce dynamic range. These are overcome by using recently available signal processing employing high frequency carrier clipping. An increase in intelligibility of speech with this HFCC has been demonstrated, for normal subjects with simulated deafness, and for most partially hearing patients. Intelligibility is not improved for some patients; possibly due to their having learned to extract features which are lost. These patients may also benefit after training.

Acoustics

Vision with isoluminant colour contrast: 1.A projection technique and observations.

An optical technique is described for projecting two-colour pictures with controlled brightness contrast, which may be set to zero-at isoluminance. Colour registration is maintained without adjustment or special setting up. It is suggested that colour-and brightness-contour registration in the visual channel is a problem which may be solved neurally be master brightness signals locking slave colour signals. The projection apparatus allows the supposed master brightness signals to be removed-at isoluminance-when contour disturbances should occur. Observation of this kind are reported.

Color Perception

Role of intragastric pressure, pH, and pepsin in gastric ulceration in the rat.

A method of continuous gastric perfusion with "artificial gastric juice" was used in a study of individual factors (intragastric pressure, pH, and pepsin) known to participate in the pathogenesis of peptic ulcers. This method allowed change of only one factor at a time, while the other two remained constant. The gastric mucosa of normal rats, fasted for 48 hr, was found to be resistant to the ulcerogenic effects of artificial gastric juice perfused through the stomach for 6 hr without increasing the intragastric pressure. Perfusion of hydrochloric acid (pH 1.3) under increasing pressure produced ulceration of the corpus as well as forestomach portion of the stomach. The degree of gastric ulceration paralleled increases in intragastric pressure, acidity, and pepsin proteolytic activity. Inhibition of pepsin activity by a pepsin inhibitor protected the gastric mucosa even at the very low pH of 1.3. These results demonstrate that under the experimental conditions used, hydrochloric acid alone in the absence of pepsin does not produce ulceration of the rat stomach.

Animals