The communication gap between a hospital's top management and the line employees need not be an ever-widening chasm. St. Luke's Hospital of Kansas City, MO, has established a system that allows administrators and employees to meet face to face every month without destroying the hospital's essential chain of command.

Communication↗

PubMedDate not supplied

Validation study for the determination of tetracycline residues in animal tissues.

An interlaboratory study of the liquid chromatographic (LC) determination of tetracyclines--oxytetracycline (OTC), tetracycline (TTC), and chlortetracycline (CTC)--in animal tissues was conducted. Isolation was performed with oxalic buffer followed by dechelation and deproteination with oxalic acid-acetonitrile. The extract was cleaned with a styrene-divinylbenzene cartridge. LC analysis was performed with a PLRP-S column and 0.01 M oxalic acid-acetonitrile (75 + 25, v/v) as mobile phase. Participants analyzed 2 control and 10 fortified porcine muscle and kidney samples. Additionally, porcine muscle samples containing incurred residues of tetracyclines were analyzed. Mean recoveries of fortified residues from porcine tissue ranged from 76.00 to 86.89%. Repeatabilities varied from 2.05% for OTC to 3.61% for TTC for muscle samples and from 6.75% for CTC to 8.74% for OTC for kidney samples. Reproducibilities ranged from 2.05 to 4.30% for muscle samples and from 15.77 to 18.81% for kidney samples.

Acetonitriles↗

PubMedDate not supplied

Changing pesticide technology in meat and poultry products.

In response to consumer concerns about pesticide residues in meat and poultry, a National Residue Program was introduced in the 1960s. Rapidly developing analytical methods and instrument capability resulted in a laboratory-based program of sufficient size and technical capability to quantitatively determine an increasing number of pesticides. In 1985, at the request of the Food Safety and Inspection Service, the National Academy of Sciences evaluated the program and recommended that more emphasis be placed on preventing residues and providing a higher degree of safety to consumers. In response, FSIS made a commitment to increase and improve capability to test for more residues, including pesticides, and to develop or purchase rapid test systems to facilitate the planned expansion of the National Residue Program. Such systems are now being evaluated and integrated into the program. Factors important for acceptability of rapid tests are reviewed in detail.

Animals↗

PubMedDate not supplied

Group dental practice in Canada--a growing trend!

Explore the source record for details and available documents.

Adult↗

PubMedDate not supplied

Chemical analysis of meat products.

Meat, particularly muscle tissue, is basically a 3-component system of protein, moisture, and fat. Although this seems a simple analytical system in which to monitor product composition for regulatory compliance, the simplicity quickly erodes when meat is formulated into the broad variety of products commercially available today. Alternative protein sources, as well as preservatives, binders, extenders, emulsifiers, spices, and other flavoring ingredients, add to the analytes of concern and highlight the need for analytical methods suitable to support inspection and labeling requirements to ensure product compliance. Some key issues are noted which involve protein quality analysis, rapid compositional analysis, isolated soy protein analysis, and minced fish in meat products.

Amino Acids↗

PubMedDate not supplied

Gas chromatographic/mass spectrometric confirmation of ten N-methylcarbamate insecticides in liver.

A gas chromatographic/mass spectrometric (GC/MS) confirmation procedure for 10 phenyl-N-methyl-carbamate insecticides in liver tissue was developed. The extract from liquid chromatography (LC) is purified with a C18 solid-phase extraction cartridge and then derivatized with heptafluorobutyric anhydride; the derivative is injected for analysis by GC/MS with electron ionization and multiple ion monitoring. The identity of the derivative is confirmed by comparison of its retention time and relative intensity data with those of a standard. Liver extracts from the LC procedure containing carbamates at 10 ppb levels were successfully confirmed by this procedure.

Animals↗

PubMedDate not supplied

Analyte stability study of N-methylcarbamate pesticides in beef and poultry liver tissues by liquid chromatography.

To optimize conditions for sample collection, preparation, storage, and analysis and to assure the validity of our previously published liquid chromatographic (LC) method for carbamate analysis in tissue, stabilities of 16 N-methylcarbamates in beef, duck, and chicken liver tissues were studied by using 2 sampling protocols. Tissue samples were fortified at room temperature to a concentration 5 to 10 times greater than either the Environmental Protection Agency tolerance level for each compound (if established) or the concentration used in the previously published method. Thereafter, samples were continuously frozen at -4 degrees C for varying time intervals. In the first study, samples were analyzed one day (initial) and 0.5, 1, 1.5, 2, 3, 4, 5, and 6 months after fortification. In the second study, samples were analyzed one day (initial) and 0.5, 1, 2, 3, and 6 months after fortification. For each residue and species, a minimum of 4 samples were analyzed by LC at each point in time, and the mean represented analyte concentration at the end of each time interval. Rates of residue depletion varied among analytes and among species. Depletion rates were greater in duck livers than in beef livers. Methomyl and oxamyl were depleted completely within 2 weeks. Between 2 and 6 months after sample fortification, residue depletions to levels below detection limits were observed for aldicarb, aldicarb sulfoxide, aldicarb sulfone, dioxacarb, promecarb, propoxur, and bendiocarb. The initial loss of certain carbamates during sample preparation in tissues exposed to room temperature for up to 8 h was greater than the subsequent rate of loss. Results indicate that cryogenic conditions are required for sample preparation and storage.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

PubMedDate not supplied

Extension of a liquid chromatographic method for N-methylcarbamate pesticides in cattle, swine, and poultry liver.

Liver samples of bovine, swine, and poultry were fortified with 0, 5, 10, and 20 ppb mixed standards of an additional 6 carbamates as part of a method extension study. Each of the 3 species in this study was analyzed 4 times at 0, 5, 10, and 20 ppb fortification levels. The average of 12 recoveries of 6 carbamates at all 3 fortification levels was greater than 90%, with a maximum coefficient of variation less than 18%.

Animals↗