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Biomedical subjects

R L Clarke

Publications and source records attributed to R L Clarke.

At least 73 records · Page 4Linked to original sources

Minimally invasive cancer surgery using focused ultrasound: a pre-clinical, normal tissue study.

Using a focused 1.7 MHz ultrasound field (focal length/transducer diameter ratio of 1.7) and in situ intensities spatially averaged within the half-pressure maximum contour in the range 100-400 W cm-2, ablative lesions have been prescriptively placed singly and in arrays, in the livers and bladder walls of adult female Large White pigs. Exposures were made through the skin with up to 8 cm of intervening tissue. Ablative lesions were placed under ultrasonic guidance, and specific lesion echoes were subsequently observed in two cases. Animals were sacrificed immediately after induction of ultrasonic lesions, post-mortems were performed, as were histological examinations of normal and damaged tissue. There was clear demarcation between ablated and normal tissue. Provided that simple rules on exposure technique had been observed, there was no evidence of inadvertent tissue damage, either locally to the treatment site, or in the tissue lying between the source and the target. This study is a useful step in demonstrating the feasibility of clinical trials for the use of this technique in treating bladder tumours and solitary liver metastases.

Animals↗

President Clinton's Health Security Act: a financial perspective.

The loftiness of President Clinton's goals may not survive the devil in the details, suggests the author of this article, who identifies four fundamental flaws in the Health Security Act of 1993. First, the act does not link the benefit package of coverage offered to all Americans with the funding available from employers or government to pay for these benefits; second, the act does not provide incentives for consumers to use health resources wisely; third, the act relies too much on government regulation; and fourth, the act provides few incentives for medical research, new drugs, and improved technology.

Computer Communication Networks↗

A new laboratory method to fabricate lower porcelain veneers.

The fabrication of porcelain veneers in the laboratory presents many problems for the technician in the production of accurate margins and contacts, good aesthetics and, in some cases, function with the opposing dentition. Therefore, a simple, accurate and previously unpublished method of producing multiple contiguous veneers is described in this paper, involving the fabrication of six lower anterior porcelain veneers in a difficult case of tooth surface loss.

Cuspid↗

Variation of Young's modulus with the test specimen's aspect ratio.

A study of Young's modulus in flexure of a number of methacrylate polymers indicated that the results were dependent on the test specimen thickness. The Young's modulus calculated from simple bending theory decreased with increased specimen thickness. This effect could not be accounted for either by the usual corrections for shear or corrections for the effect of the width/length ratio. It transpires that the effects noted experimentally are due to the combined effects of shear and the width/length ratio.

Denture Bases↗

Modified Arrhenius equation for the frequency dependence of the transition temperature of polymers--a note on some further observations.

Activation energies obtained from differential mechanical thermal analysis work on polymers have been observed to relate to similar behaviour of diffusion coefficients of gases in polymers. Comparison of the two techniques showed the additional energy terms to be virtually identical and the pre-exponential factors to relate to segmental motion of a five-unit carbon atom.

Biocompatible Materials↗

Shifting no solution to problem of increasing costs.

Rising healthcare costs are being allocated unevenly because some stakeholders are better than others at insulating themselves from paying their share of the burden. Those with significant or group purchasing power are paying less than actual cost, forcing providers to shift a disproportionate share of the costs to small businesses and non-group purchasers. The magnitude of this cost shifting is large and growing. Its primary impact is a destabilization of insurance markets. Stability can only be restored with well thought-out proposals that deal with causes of the cost increases.

Cost Allocation↗

What do you know?

Available data don't tell us enough about costs, trends or utilization patterns to guide efforts at reform of the system.

Centers for Medicare and Medicaid Services, U.S.↗

A quality fad?

Explore the source record for details and available documents.

Hospital Administration↗

Panel sees high demand for diverse CFO skills.

A more sophisticated healthcare industry, challenged by competition and payer demands, also looks for sophistication when filling its senior financial positions. Individuals with experience in managed care contract negotiations, knowledge of hospital-physician ventures, and superior planning and treasury management skills are increasingly sought by hospitals. Some organizations also may single out chief financial officers able to assume broader administrative duties, including chief executive officer positions. These are among the observations of a panel convened by HFMA to discuss recent trends in healthcare executive recruiting. Highlights of the session, moderated by HFMA President Richard L. Clarke, FHFMA, follow.

Employment↗