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Biomedical subjects

R L Binder

Publications and source records attributed to R L Binder.

92 records · Page 6Linked to original sources

Purification of beta-N-acetyl-D-glucosaminidase of the horseshoe crab by affinity chromatography.

An affinity column has been synthesized consisting of p-aminophenyl 1-thio-beta-L-fucopyranoside residues attached to Sepharose 4B through succinylated diaminodipropylamine bridges. Surprisingly, it has been found to bind beta-N-acetylglucosaminidase in the serum of Limulus polyphemus (horseshoe crab). The enzyme is eluted with N-acetyl-D-glucosamine at a concentration of 2 mg/ml and with other sugars at higher concentrations. A highly purified enzyme free from other glycosidases is obtained. The enzyme is not eluted by solutions of salt.

Acetylglucosaminidase↗

Physical complaints without organic basis in psychiatric inpatients: report of two cases.

Two patients with borderline personality disorder hospitalized for behavior disturbance had physical complaints for which no organic basis could be found. These cases highlight a conceptual difficulty in our current classification system for such physical complaints, raise issues about the interplay of psychiatric syndromes, and illustrate how physical complaints without organic basis complicate psychiatric hospitalization.

Adult↗