Search PubMed⌕ Search

Biomedical subjects

R Kraft

Publications and source records attributed to R Kraft.

193 records · Page 11Linked to original sources
PubMedDate not supplied

[Effect of risk factors and therapy on intermediate-term hip deformity in Perthes disease].

UNLABELLED: The prognostication of risk factors for the outcome of LCPD was examined. The radiographic results of conservative treatment with Thomas splint and operative treatment with intertrochanteric derotational varus osteotomy (DVO) were compared using the Index of Deformity (D). METHOD: Radiographs of 153 patients with unilateral LCPD were evaluated retrospectively 1.5-3 years and 3-7 years after diagnosis using the Index of Deformity and Index of Direction. We investigated the radiographic changes in relation to acetabular or metaphyseal reaction, Waldenström classification or limited range of motion at diagnosis and in dependence of therapy. RESULTS: There was a significant better acetabulum-head-index of deformity after DVO. Children with metaphyseal or acetabular reaction had bigger deformities. Patients with metaphyseal reaction had smaller deformities after DVO compared with conservative treatment. Free range of motion (ROM) was prerequisite for good results after DVO. Waldenström classification at diagnosis did not have any influence on morphologic changes after 3-7 years. CONCLUSION: DVO leads to a better containment than conservative treatment with Thomas splint, metaphyseal reaction should be an indication for operative treatment. Prerequisite for DVO is a free ROM. Because Waldenström class at diagnosis does not influence the outcome, free ROM before starting the treatment is more important than an immediate start of therapy.

Adolescent↗
PubMedDate not supplied

Glyceraldehyde-3-phosphate dehydrogenase is responsible for intranuclear localization of some oligonucleotides.

Nuclear accumulation of ODNs has been associated with their binding to a series of nuclear proteins. These interactions could be responsible for the sequence-independent effects of ODNs as well as for their sequence-specific interactions and their intracellular distribution. Investigation of interaction of ODNs with these proteins may shed light on the mechanisms of cellular uptake and nuclear accumulation of oligonucleotides.

Binding, Competitive↗
PubMedDate not supplied

Nonasbestos ferruginous bodies in sputum from a patient with graphite pneumoconiosis: a case report.

BACKGROUND: Inhalation of graphite dust can cause lung disease, mostly in the form of mixed-dust pneumoconiosis in individuals working in the metallurgic industry or graphite mines. The morphologic landmark of graphite pneumoconiosis is nonasbestos ferruginous bodies with a black graphite core. CASE: In the sputum of an 81-year-old male, characteristic nonasbestos ferruginous bodies were identified. The occupational history confirmed long exposure to natural graphite in metallurgy. CONCLUSION: By the identification of typical ferruginous bodies, the screening of sputum smears may confirm the clinical and radiologic suspicion of pneumoconiosis and may contribute to determining its causes.

Aged↗