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Biomedical subjects

R Kopher

Publications and source records attributed to R Kopher.

3 recordsLinked to original sources

Decrease in the rate of ruptured ectopic pregnancies: a successful team approach.

Noting the increasing frequency of ectopic pregnancy and desiring to reduce both morbidity and mortality, OB/GYN physicians at a large midwestern HMO systematically monitored all ectopic pregnancies in their clinical practice as the first step in a quality improvement project. Data were collected on several components of care including access, risk assessment, diagnosis of ectopic pregnancy, and intervention. To ensure the system was able to coordinate new diagnostic and therapeutic modalities, several key initiatives were instituted to improve patient outcomes. These included application of comprehensive guidelines, increased ultrasound availability, and increased staff and patient awareness. Following the implementation of the initiatives, there was a decrease in rupture rates from 32% in 1988 to 5% in 1992. This paper discusses the development and integration of the initiatives into the staff model HMO.

Algorithms↗

Endpoints of chronobiologic cardiovascular monitoring during pregnancy for planning exercise and assessing effects.

The chronobiologic question is raised whether exercise may be indicated for the pregnant woman as a general prophylactic measure and, if so, whether it should be timed according to rhythms and stage of pregnancy. This question, recently considered by others without chronobiologic focus, is here reviewed against the background of results from ongoing chronobiologic studies of blood pressure (BP) and heart rate (HR) in pregnancy. During pregnancy, the MESORs and circadian amplitudes of systolic (S), mean arterial (MA) and diastolic (D) BP are correlated with a questionnaire-assessed cardiovascular risk score. Such results were found under noisy ordinary conditions of life without accounting for effects of activity. They are group results, and as such require further work before they can contribute to identifying individuals at high risk in particular need of intervention, such as exercise. The dependence of exercise effects upon circadian rhythms should also prompt the use of rhythmometry at all ages for timing exercise, for gauging its effects and eventually for the optimization of fitness training for the population as well as for peak performance.

Blood Pressure↗