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Biomedical subjects

R Knopp

Publications and source records attributed to R Knopp.

At least 91 records · Page 5Linked to original sources

[Functional scintigraphy during contraction of the left ventricle. III. Findings in patients with coronary heart disease (author's transl)].

Left ventricular volume curves were measured by a noninvasive technique after equilibration of 99m TC human serum albumin in 27 patients with angiographically proven coronary heart disease. Compared with normals, patients with coronary insufficiency showed a significant reduction in the ejection fraction and of maximal emptying and filling times of the left ventricle during rest. In mildly affected patients with normal ejection fractions, maximal filling was already reduced in keeping with the well known loss of compliance of the left ventricle due to coronary disease.

Cardiac Volume↗

[Electronic data processing in the clinical nuclear medicine].

Computer techniques as introduced into clinical nuclear-medicine 12 years ago, were first exclusively used for scintigraphic purposes. Through the development of a comprehensive pilot system for nuclear medical data processing on the basis of two Siemens Process control computers it could be demonstrated, that besides of scintigraphy there are also other important fields for computer application, e.g. in function diagnostics and therapy planning.

Bayes Theorem↗

Central venous cannulation and pressure monitoring.

Central venous pressure (CVP) varies directly with circulating blood volume and vascular tone and inversely with right heart competency. Indications for central cannulation include cardiorespiratory arrest. The two general approaches to cannulation of central veins are peripheral and central. The physician's skill, patient's body habitus, clinical circumstances, age and thoracic deformity all influence the choice of technique. Three of the possible complications discussed are pneumothorax, arterial puncture and air embolus. Accurate measurement of CVP depends on the patient being supine, a patent and accurately located catheter and the establishment of a baseline external zero point.

Carotid Artery Injuries↗

[Sequential hepato-splenic scintigraphy for measurement of hepatic blood flow (author's transl)].

The arterial and portal components of total liver blood flow were determined quantitatively in 31 patients by means of a new, non-invasive method. Sequential hepato-splenic scintigraphy has been employed, using a scintillation camera linked to a computer system. In normals, the proportion of portal flow was 71%, whereas in patients with portal hypertension it averaged 21%. Our experience indicates that the procedure can be of considerable value in the pre-operative diagnosis and postoperative follow-up of portal hypertension.

Adolescent↗

[Hepatobiliary scintigraphy with (99m)Tc-diethyl-IDA (author's transl)].

A short description of the pharmacology and kinetics of (99m)Tc-diethyl-IDA is given; our experience with this new radiopharmaceutical as a functional test of liver and bile ducts is illustrated by a number of typical examples. The ability to use increased activity together with high resolution "low energy" detectors provides excellent detail recognition in the hepato-biliary system. In addition, sequential scintigraphy with its resulting time-activity curves provides information regarding the function of the hepatocytes. The significance of hepatobiliary scintigraphy is its ability to distinguish between parenchymal and obstructive jaundice.

Acetanilides↗

Medical control. Quality assurance in prehospital care.

Medical control is an essential component of a prehospital care system. It is a method of ensuring quality and accountability of the care provided and thus provides a method of risk management for the system. Politicians, fire departments, ambulance companies, physicians, and others are struggling for control of prehospital emergency care. Unless physicians are willing to become involved and provide leadership for prehospital care, it will be impossible to establish quality care. Physician input must be involved throughout planning, implementation, and evaluation of an EMS system. It is mandatory that physicians experienced in emergency care of the acutely ill or injured patient direct all medical aspects of the prehospital care system and provide ongoing review of the system. Medical control includes three phases: prospective, immediate, and retrospective. The incorporation of medical control in a specific EMS system will be dependent on that system's characteristics; nevertheless, proper medical control is essential to ensure a high quality of prehospital care. Further studies will be necessary to evaluate medical control and determine the best mechanism for providing quality assurance in prehospital care.

Administrative Personnel↗