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Biomedical subjects

R Kind

Publications and source records attributed to R Kind.

47 records · Page 3Linked to original sources
PubMed1976

[Thévenard ulcero-mutilating acro-osteopathy syndrome].

A 20-year old female patient with characteristic symptoms of acroosteolysis of the left foot (sensory neuropathy, ulcers and hyperkeratosis on the acra, acroosteolysis and peroneal muscleatrophy) is described. The syndrome manifested in early childhood, heridity could not be found. Correspondence to the familial type of acroosteolysis (of Thevenard) as a new mutation is discussed.

Adult↗
PubMed1976

[Clinical picture of pretibial myxedema and new aspects of diagnosis and pathogenesis].

We have reported on two cases of pretibial myxedema. In one patient, the pretibial myxedema developed symmetrically half a year after the appearance of endocrine exophthalmos. Recently, acropachy developed as well. In the second case, the pretibial myxedema arose unilaterally in an old cicatricial area, six years after the onset of endocrine exophthalmos. In this syndrome, the development of the whole group of symptoms, dermopathy, ophthalmopathy, and osteopathy at the same time is very rare. The clinical picture is seen in thyroid disorders, as a rule occuring in hyperthyroidism, rarely in hypothyroid or euthyroid states. Apparently, the development of the symptoms does not depend on thyroid hormone production. One of our patients showed conspicuous hyperthyroidism, the other, thyroxin deficiency. The thyreohypophyseal feedback mechanism in this syndrome was examined for the first time by means of TRH stimulation tests. In both patients, thyroid auto-antibodies indicative of autoimmune thyroiditis were demonstrated. A high activity of long acting thyroid stimulator was measured in the one patient's serum.

Adult↗
PubMed1975

[Acro-osteolysis (acro-osteopathia ulcero-mutilans) in a worker exposed to vapours of synthetics (author's transl)].

The neuro-cutaneo-osseous syndrome of "sporadic" acrosteolysis (of Bureau-Barrière), localized to the ends of the feet, has occasionally been seen in workers engaged in the polymerization of vinyl chloride, A case of the disease is described in a 42-year-old worker exposed to different vapours during the manufacture of plastic products, but he had never worked with vinyl chloride. Outstanding signs were dysproteinaemia, moderate thrombocytopenia, while symptoms of Raynaud's disease as well as scleroderma-like changes in hands and feet (typical of vinyl chloride disease) were absent. The onset of the osteolytic and ulcerative process corresponded to prolonged exposure to cold on the job. It is, therefore, assumed that there was concealed chronic intoxication with synthetic vapours which, in connection with cold exposure and other individual factors, may have aided in the manifestation of the disease. It is possible that under certain conditions synthetics other than vinyl chloride may contribute to the occurrence of sporadic cases of acro-osteolysis.

Adult↗
PubMed1975

[The bullous variant of erythema annulare centrifugum Darier in Candida albicans infections].

A 15-year old male patient with Down-Syndrome suffering from a unusual vesicular type of erythema annular centrifugum Darier and a concurrent intestinal infection with candida albicans is described. Histology, immunhistological assay, and clinical observation allowed to differentiate Erythema annulare centrifugum from erythema exsudativum multiforme as well as dermatitis herpetiformis. On the basis of immunological findings and the clinical course, a hypersensitivity to candida albicans like a so-called "id-reaction" is assumed to be the main etiological factor in this case.

Adolescent↗
PubMedDate not supplied

Subduction and collision processes in the Central Andes constrained by converted seismic phases.

The Central Andes are the Earth's highest mountain belt formed by ocean-continent collision. Most of this uplift is thought to have occurred in the past 20 Myr, owing mainly to thickening of the continental crust, dominated by tectonic shortening. Here we use P-to-S (compressional-to-shear) converted teleseismic waves observed on several temporary networks in the Central Andes to image the deep structure associated with these tectonic processes. We find that the Moho (the Mohorovicić discontinuity--generally thought to separate crust from mantle) ranges from a depth of 75 km under the Altiplano plateau to 50 km beneath the 4-km-high Puna plateau. This relatively thin crust below such a high-elevation region indicates that thinning of the lithospheric mantle may have contributed to the uplift of the Puna plateau. We have also imaged the subducted crust of the Nazca oceanic plate down to 120 km depth, where it becomes invisible to converted teleseismic waves, probably owing to completion of the gabbro-eclogite transformation; this is direct evidence for the presence of kinetically delayed metamorphic reactions in subducting plates. Most of the intermediate-depth seismicity in the subducting plate stops at 120 km depth as well, suggesting a relation with this transformation. We see an intracrustal low-velocity zone, 10-20 km thick, below the entire Altiplano and Puna plateaux, which we interpret as a zone of continuing metamorphism and partial melting that decouples upper-crustal imbrication from lower-crustal thickening.

Journal Article↗
PubMedDate not supplied

[Acute hemorrhage caused by duodenal ulcer. Results of endoscopic treatment of the first bleeding episode and of recurrences].

BACKGROUND: The aim of this study was to evaluate the impact of immediate endoscopic treatment of bleeding and rebleeding on the clinical outcome of patients with duodenal ulcer hemorrhage. MATERIALS AND METHODS: Between January 1995 and December 1998, 445 patients with bleeding duodenal ulcers were observed in the First Division of General Surgery--University of Verona. All patients, except two who died for hemorrhage before the endoscopic examination, underwent emergency endoscopy within 2 hours from the admission and ulcers with active or sign of recent bleeding were submitted to injection therapy. History, clinical and endoscopic findings, recurrent bleeding and outcome were prospectively collected and analyzed. Recurrent bleeding underwent immediate endoscopic retreatment as first attempt. RESULTS: Endoscopic therapy was performed in 277 patients with active bleeding and hemostasis was initially obtained in all patients except one. Rebleeding occurred in 62 patients (14%) and endoscopic treatment was successful in 85% of first rebleeding and in 58% of the cases with 2 or more rebleeding. Multivariate analysis showed that systolic blood pressure at admission, ulcer size and Forrest classification influenced independently the recurrence rate. The 30 days mortality was 12.2% in the whole series: 35 deaths (9.2%) in the group without recurrence and 19 (30.6%) deaths in the rebleeding group (p = 0.001). Only 22 patients (5%) underwent surgical treatment with a higher mortality compared to not operated patients (36.4% versus 10.9%). CONCLUSIONS: Endoscopic treatment was associated with reductions of the risk of recurrent bleeding and surgery without increasing mortality rate.

Acute Disease↗