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Biomedical subjects

R Kapoor

Publications and source records attributed to R Kapoor.

263 records · Page 15Linked to original sources
PubMedDate not supplied

Response of lung transfer components to grades of smoking.

Pulmonary functions were studied in 50 healthy, asymptomatic, 20 to 47 years, male smokers along with 50 healthy non-smokers matched for age, height, socio-economic status and physical activity. Smokers consumed 2-30 cigarettes per day with duration of smoking ranging from 2 to 26 years. In smokers FEF, V75. PEF and MVV were significantly reduced whereas FRC was increased significantly. Pulmonary diffusion function as assessed by TLCO showed significant reduction. While Vc showed progressive decrease with increasing duration and quantity of smoking, DM increased in the beginning but gradually declined later. TLCO showed a better negative correlation with quantity than with duration of smoking even when the effect of other factors was excluded. Decrease in TLCO is probably due to bronchoconstriction and reflex vasospasm of pulmonary vasculature. Co-efficient of diffusion KCO was also decreased in smokers.

Adult↗
PubMedDate not supplied

Ventilatory and diffusion studies in smoker and non smoker flour-mill workers.

Various pulmonary function tests, FVC, FEV1/FVC%, PEFR, EFR25-75, MVV and Tlco were measured in 25 asymptomatic male flour mill workers and 50 healthy subjects not working at flour mill, to assess the effect of flour dust on lungs. All the subjects of different groups were well matched in their anthropometeric parameters and socio economic status. In smoker flour mill workers significant reduction was present in both ventilatory and diffusion functions of lungs, which was more pronounced in subjects who consumed larger quantity of tobacco and were exposed to flour dust for longer duration. On the other hand deterioration of pulmonary functions in non smoker flour mill workers was found to be statistically not significant. The relative strength of both the parameters viz tobacco and flour dust for impairment of pulmonary functions is discussed for being a pointer to further studies.

Adult↗
PubMedDate not supplied

Polarized light microscopic examination of human bile in the diagnosis of microlithiasis of the gallbladder.

Of the 20 cases with biliary colics who had normal OCG and ultrasound, 11 (55%) showed microlithiasis in the form of cholesterol monohydrate crystals and/or calcium bilirubinate granules on polarized light microscopy of the duodenal bile. Microlithiasis was noted in gallbladder bile of all (100%) the cases with proven gallstones but in none of the duodenal bile samples from healthy subjects. This study suggests that polarized microscopy may be a useful method to detect microlithiasis in patients with repeated biliary colics who have normal OCG and ultrasound examination.

Bile↗
PubMedDate not supplied

Pulmonary diffusion capacity for Co at varying alveolar oxygen tensions and different alveolar volumes.

In six healthy nonsmoker volunteers pulmonary diffusion capacity for Co (DLCO) was determined by single breath holding technique. Multiple measurements of DLCO were taken with PAO2 from 70 to 610 mm Hg, out of which at least 10 tests were performed between 100 to 140 mm Hg. A wide and non uniform inverse relationship was found between DLCO and PAO2 from 70 to 610 mm Hg. In narrow range of 100-140 mm Hg, a highly significant linear negative correlation was found. To find out corrected DLCO at PAO2 120 mm Hg, expressed as DLCO120, a correction factor of 0.45% for each mm Hg change in PAO2 should be applied to measured DLCO inversely. By regulating inspiratory volume, DLCO was studied at different alveolar volumes and there was a direct positive correlation between them. DLCO should be measured at maximum alveolar volume, as with one percent fall in VA there is 0.69% decrease in DLCO. This new method of expressing DLCO as DLCO120 at maximal effective alveolar volume will be more useful in studying the effects of factors affecting DLCO and for interlaboratory comparison.

Adult↗
PubMedDate not supplied

Hemangioendothelioma. Cytologic appearances in two cases presenting with multiple soft tissue and bone lesions.

Two cases of hemangioendothelioma were detected by fine needle aspiration cytology in two women presenting with multiple soft tissue and bone lesions. The aspirates were hemorrhagic, and the smears showed mostly dissociated and predominantly monomorphic tumor cells. Focal rosettelike clustering of tumor cells was also present. A prominent cytologic feature of these two cases of hemangioendothelioma was the close association of tumor cells with endothelium-lined vascular structures, a pattern that can be seen in other sarcomas and sometimes in malignant epithelial tumors.

Adult↗