Pralidoxime for reducing nicotinic cholinergic morbidity in organophosphate poisoning.
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Biomedical subjects
Publications and source records attributed to R K Patial.
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A case of vivax malaria with neurological symptoms is described.
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Five patients of hyperthyroidism with Motor Neurone Disease like picture seen over a span of five years are described. The illness was of over 3 years duration and all patients were males. One patient had even the diagnosis of "MND'. It took 1 to 3 months for disappearance of MND picture with antithyroid drugs. In MND like disease every effort should be made to exclude hyperthyroidism.
Four patients of pure gouty nephropathy are presented. Gout was of over five years duration and asymptomatic nephropathy manifested as non-oliguric acute renal failure. Diseases commonly associated with it like uric acid stones, urinary tract infections, hypertension, diabetes mellitus, hyperlipidemid, obesity and nephrosclerosis were absent. Reduction in serum uric acid level resulted in prompt improvement in renal functions. Early detection and control of hyperuricemia may help in restoration of renal functions.
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The role of real-time ultrasonography was evaluated in 50 randomly selected cases with a strong clinical suspicion of gallbladder diseases and normal oral cholecystogram. Of these, 13(26%) cases showed abnormalities on ultrasonography.
Neurological complications like type II paralysis are well described in organophosphorus poisoning. Sphincteric involvement is not described. We report two patients of organophosphorus poisoning who had sphincteric involvement as an unusual manifestation of type II paralysis.
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Electrocardiographic monitoring of a 24 year old male, who sustained household electric current injury, showed low voltage ECG complexes, varying degrees of atrioventricular (AV) blocks, and ventricular fibrillation. The low voltage ECG complexes and varying AV blocks disappeared spontaneously and ventricular fibrillation reverted to normal after cardioversion.
A patient with Lyme disease is described. He presented with meningitis-like picture, arthritis, and carditis (congestive cardiac failure and variable AV blocks without valvular lesions). Borrelia was present in the peripheral blood smear.
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Two cases with severe hypoglycaemia following zinc phosphide poisoning are reported. Both patients succumbed to toxic myocarditis.
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