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Biomedical subjects

R K Pandhi

Publications and source records attributed to R K Pandhi.

53 records · Page 3Linked to original sources
PubMed1975

The effects of some hair oils and unsaturated fatty acids on experimentally induced dermatophytosis.

Antimycotic effect of mustard and coconut oils, oleic and palmitic acids on experimentally produced dermatophytic infection on hairy skin in the guinea pigs was studied. Mean Duration of Infection (MDI) was significantly reduced in all experiments where coconut and mustard oils or unsaturated fatty acid (oleic acid) were used. The significance of these results in realtion to Tinea capitis in humans is discussed.

Animals↗
PubMed1975

A study of the immunological status of patients with dermatophytoses.

22 patients with Trichophyton rubrum infection were studied for some of their immunological parameters. The trichophytin skin test performed with commercially available Dermatophytin (Hollister-Stier) gave immediate positive reaction in 3 patients. All the other patients gave negative delayed and retarded reactions. In vitro response to PHA of the peripheral lymphocytes was significantly depressed in patients compared to the controls. No relationship could, however, be established between the severity, duration or extent of the disease and the depression of the lymphocyte response. IgG and IfA were found to be within normal limits. IgM levels were significantly depressed which was probably artefactual in nature.

Humans↗
PubMedDate not supplied

Fixed drug eruptions on male genitalia: clinical and etiologic study.

Fixed drug eruptions exclusively involving the genitalia of 60 male patients were investigated. Forty-two of the 60 patients completed tests designed to identify the causative drug. Tetracycline, aspirin, metamizole, and trimethoprim-sulfamethoxazole were found to be common etiologic agents. The sites affected were the glans penis, coronal sulcus, and preputial skin. Superficial ulceration or pigmented areas surrounded by an erythematous halo were the main clinical findings at the time of presentation.

Anti-Infective Agents↗
PubMedDate not supplied

Post-kala-azar dermal leishmaniasis: a histopathological study.

BACKGROUND: Post-kala-azar dermal leishmaniasis follows an attack of visceral leishmaniasis and is caused by the same organism, i.e. Leishmania donovani. METHODS: In the present study, biopsy specimens from hypopigmented macules, nodules or plaques of 25 patients clinically diagnosed as PKDL were evaluated for epidermal and dermal changes and for the presence or absence of Leishmania donovani bodies (LDBs). RESULTS: The hypopigmented macules showed a patchy perivascular and periappendageal infiltrate with no demonstrable LDBs in any of the biopsies. In the nodular and plaque lesions, the infiltrate was diffuse, beneath an atrophic epidermis (74%) and follicular plugging (95.6%) was seen in most biopsies. The infiltrate consisted of lymphocytes, histiocytes and plasma cells in decreasing order of presence. LDBs could be demonstrated in only 10 (43.5%) biopsy specimens from nodular and plaque lesions and were never numerous. CONCLUSIONS: Histopathological features of PKDL are elucidated and discussed.

Adolescent↗
PubMedDate not supplied

Hepatic ultrasonography in patients with lepromatous leprosy.

Hepatic Sonography was done in 36 patients with lepromatous Leprosy and 3 patients with borderline lepromatous leprosy with the view to assess abnormalities of size, changes in the echotexture and to observe the presence of any nodules and calcification in the liver. Routine liver function tests were also done in these patients. No definite abnormal sonographic findings were seen in the liver in a large majority of these patients. One patient, however, showed nodular changes in the liver.

Adult↗
PubMedDate not supplied

Leprosy in resettlement colonies of Delhi.

Population influx into urban areas like Delhi has encouraged mushrooming of numerous slums where about 30% population of the city is living. A survey was conducted in four resettlement colonies of Delhi. Of the 6,876 persons examined, 43 (6.25 per 1000) subjects were found to have clinical and histologic evidence of leprosy. Fifteen (35%) patients of neuritic leprosy, eight (19%) with tuberculoid leprosy, 12 (38%) of borderline tuberculoid, three (4%) each with borderline and borderline lepromatous and one (2%) each of lepromatous and indeterminate leprosy were diagnosed. The study revealed that 21% of the patients were less than 20 years of age.

Adolescent↗