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Biomedical subjects

R K Forster

Publications and source records attributed to R K Forster.

87 records · Page 5Linked to original sources

Therapeutic surgery in failures of medical treatment for fungal keratitis.

Medical treatment failure necessitated surgery in nine cases of fungal keratitis. Therapeutic surgery eliminated fungal infection in seven cases, and useful vision was retained in five out of six penetrating keratoplasties. In three cases Natamycin (Pimaricin) therapy rendered fungi non-viable, but two were demonstrable by histopathology. These results suggest that antifungal treatment should be applied for as long as possible before therapeutic surgery in order to improve the final visual outcome.

Conjunctiva↗

Dematiaceous fungal keratitis. Clinical isolates and management.

Clinical and laboratory features of 16 cases of keratitis that were caused by dematiaceous pigmented fungi are reported. Management, including the treatment of nine cases with Natamycin (Pimaricin), resulted in corneal healing in 14 cases, and therapeutic surgery in two cases.

Administration, Topical↗

Further observations on the diagnosis, etiology, and treatment of endophthalmitis.

This report of 54 suspected cases of endophthalmitis emphasizes the following findings: 1. That vitreous aspiration is more sensitive in making a culture proven diagnosis than anterior chamber paracentesis. 2. That Staphylococcus epidermidis is a much more common cause of endophthalmitis than previously apprediated. 3. That intraocular antibiotics in the recommended dosage, are reasonably safe clinically and add a new dimension to the treatment of endophthalmitis.

Anterior Chamber↗

Gonococcal keratoconjunctivitis.

Gonococcal keratoconjunctivitis is a potentially devastating infection, because Neisseria gonorrhoeae can cause a rapid, severe, ulcerative keratitis resulting in visual loss. The therapeutic decision making process is complicated by the necessity for prompt, effective parenteral therapy, frequent coinfection with other sexually transmitted diseases, and emergence of antibiotic resistance. Because of the evolving problem of antibiotic resistance and the need for cost containment, the current recommendations of hospitalization for intravenous penicillin may need to be modified. The third generation cephalosporin, ceftriaxone, has properties that suggest it may be the best available antimicrobial agent as a single-dose treatment of gonococcal conjunctivitis. Spectinomycin may be a useful alternative in the penicillin-allergic adult patient.

Adult↗

Posterior polymorphous corneal dystrophy.

Cornea and iris from a 58-year-old man with posterior polymorphous corneal dystrophy were examined by light and electron microscopy. The patient is the son of a woman who was reported previously to have Chandler's syndrome. Clinicopathologic features in the two diseases are discussed in light of controversies surrounding their differential diagnosis.

Corneal Diseases↗