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Biomedical subjects

R K Chin

Publications and source records attributed to R K Chin.

46 records · Page 3Linked to original sources

Labour-related eclampsia.

Twenty-four cases of eclampsia managed in a hospital in Hong Kong over a five-year period were reviewed. Four patients had antepartum eclampsia and one had postpartum eclampsia following elective caesarean section. Four of these five patients had severe pregnancy-induced hypertension (PIH) (greater than 160/100 mmHg). The other 19 patients had eclampsia occurring during labour or within six hours of delivery. This group included 10 patients with labour-onset PIH, none of whom developed severe hypertension before their convulsions. In the remaining nine patients, only five had severe hypertension before convulsion. The results suggest that labour-related eclampsia has become more common than antepartum eclampsia, and severe hypertension before convulsion is an infrequent finding and therefore an unreliable sign in these patients.

Adult↗

Intrapartum fluid administration and sodium concentration in maternal and umbilical cord plasma.

Maternal and umbilical cord plasma sodium concentrations at delivery following routine labour ward management in uncomplicated pregnancies were studied. Three groups, each consisting of 16 patients, were recruited during labour. One group received 5% dextrose solution for administration of oxytocin. Another group received Hartmann's solution with epidural analgesia. The remaining group received no fluid (controls). There was no difference in the maternal and umbilical cord plasma sodium concentrations between patients who received 5% dextrose solution or Hartmann's solution and controls. Mild hyponatraemia (plasma sodium between 131 and 134 mmol/l) was common in all groups of mothers but severe hyponatraemia (less than 130 mmol/L) was rare. Similarly transplacental hyponatraemia was uncommon. There was no correlation between maternal plasma sodium concentration and the amount of fluid given. It was concluded that intravenous 5% dextrose solution and Hartmann's solution given during labour would not lead to significant hyponatraemia in the mother or fetus if the volume given was less than 0.6 litre.

Female↗

Is X-ray pelvimetry useful in a trial of labour after caesarean section?

In a trial of labour after caesarean section, X-ray pelvimetry has generally been regarded as an important part in the evaluation of patients before a decision is made. A review of 445 patients with trial of labour has shown that although the measurements of the pelvic inlet were greater in patients who delivered vaginally, the incidence of successful trial was not related to the measurements of the pelvis. Maternal height was also unrelated to the outcome. Only a history of previous vaginal delivery was predictive of a successful trial. The results suggest that X-ray pelvimetry is not necessary in the majority of patients if the past obstetric history and the clinical assessment are in favour of a successful trial. It is only useful when there is doubt and in this case both a lateral and an antero-posterior film are necessary as the obstetric conjugate alone was unreliable in predicting the transverse diameter of the inlet as well as the outcome.

Cesarean Section↗

The outcome of hyperemetic pregnancies complicated by transient hyperthyroidism.

Thirty-nine patients presenting with hyperemesis gravidarum were studied and the subsequent course and outcome of pregnancy between patients with normal and abnormal thyroid function was compared. Seventeen patients (43.6%) developed transient hyperthyroidism, for which a short course of antithyroid treatment was required in 2 patients. There was no difference in the outcome of pregnancy between patients with normal and abnormal thyroid function. The results suggest that while antithyroid treatment is effective for symptomatic control, it is unnecessary in the majority of patients since the condition is self-limiting, and the outcome of pregnancy not adversely affected by the transient hyperthyroidism in hyperemetic patients.

Adult↗

Effects of intrapartum intravenous infusion of 5% dextrose or Hartmann's solution on maternal and cord blood glucose.

The effects of intrapartum infusion of dextrose or Hartmann's solution on maternal and cord blood glucose were studied. Patients with and without infusion of intravenous fluids during labor were randomly selected and allocated to one of three groups. Group I received 5% dextrose solution as a vehicle for oxytocin (dextrose group), group II received Hartmann's solution (Hartmann group) and group III did not receive any intravenous infusion (control group). Each group consisted of 16 patients. Routine labor ward procedures were followed. Maternal and cord blood samples were taken at delivery. Maternal blood glucose concentrations were significantly lower in the Hartmann group than in the dextrose and control groups, showing a dilution effect of Hartmann's solution. Cord blood glucose concentrations did not differ significantly between the three groups, indicating that maternal infusion of dextrose or Hartmann's solution in routine intrapartum management would have no adverse effects on fetal blood glucose.

Adult↗

Administrative reports for monitoring pharmacy purchasing.

The use of administrative reports in a hospital pharmacy department to monitor communication regarding drug supply problems and to assist pharmacy administration in assessing the performance of its purchasing area is described. The weekly drug supply problems report was developed as a method to communicate problems in the storeroom to other pharmacy areas. The weekly borrow and loan report, which accounts for all borrow and loan transactions, helps determine the proper reorder quantities of drug products borrowed frequently and monitors repayment for loaned items. The inventory assessment report is prepared annually; in this report, drug expenditures for a "market-basket" list of drug products are compared for the current and previous years. To assess the use of nonformulary drugs, a quarterly report of expenditures for nonformulary drugs is compiled. The purchasing pharmacist, who is responsible for inventory control, prepares these reports. When considered in relation to the budget and workload statistics, the reports can be used to assess the performance of the purchasing area. Increased accountability and more orderly operation of the purchasing area has accompanied the use of these reports.

Chicago↗