Search PubMed⌕ Search

Biomedical subjects

R K Aggarwal

Publications and source records attributed to R K Aggarwal.

65 records · Page 4Linked to original sources

A multi-spectral approach for scene analysis of cervical cytology smears.

A multi-spectral approach for the scene analysis of cervical cytology smears, using multiple images of a scene digitized through suitably chosen color filters matched to the Papanicolaou stain, has been proposed here. This technique involves clustering of two-dimensional data for extracting cytoplasm of the epithelial cells. Its performance on an experimental data set of 233 scenes involving more than 10 types of normal and malignant epithelial cells has been compared with density and gradient thresholding techniques. This resulted in an approximate 83% rate of success compared to approximately 40% for the rest of the other techniques.

Cell Nucleus↗

Image processing for automated erythrocyte classification.

Digital image processing and pattern recognition techniques were applied to determine the feasibility of a natural n-space subgrouping of normal and abnormal peripheral blood erythrocytes into well separated categories. The data consisted of 325 digitized red cells from 11 different cell classes. The analysis resulted in five features: (a) size, (b) roundness, (c) spicularity, (d) eccentricity and (e) central gray level distribution. These features separated the data into six distinct condensed subgroups of red cells. Each subgroup consisted of morphologically similar cells: (a) macrocytes, (b) normocytes, (c) schistocytes, acanthocytes and burr cells, (d) microcytes and spherocytes, (e) elliptocytes, sickle cells and pencil forms and (f) target cells. The concept of a quantitative "red cell differential" was introduced, utilizing these subgroup definitions to establish subpopulations of red cells, with quantifiable indices for the diagnosis of anemia, at the specimen level.

Autoanalysis↗

Miliary mottling in non-Hodgkins lymphoma.

Pulmonary parenchymal involvement and mediastinal lymphadenopathy are less common manifestations of non-Hodgkin's lymphoma as compared to Hodgkin's lymphoma. The pattern of pulmonary disease varies with histological type of non-Hodgkin's lymphoma. We are presenting an uncommon case of diffuse histiocytic lymphoma having miliary mottling who responded well to chemotherapy.

Humans↗