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R Jones

Publications and source records attributed to R Jones.

At least 1,153 records · Page 64Linked to original sources
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Accuracy relationship of blood pressure devices between the AAMI SP 10 standard and the British Hypertension Society protocols.

This article analyzes and compares the accuracy requirements for the AAMI SP10 standard and the British Hypertension Society (BHS) protocol for evaluation of blood pressure devices. It generates a theoretical mapping relationship between the AAMI accuracy criteria and the BHS grading system, using these requirements. It locates within that relationship the analyses of blood pressure devices in the literature that have used both of these standards from 1990, when the original BHS protocol was published and the original AAMI SP10 standard was available, through the end of 1997. Comparison of 67 paired entries thus provides a framework for consideration of the concept of accuracy implicit in both systems against empirical testing of devices. Results of accuracy testing with each of the two systems should be consistent and convertible to the other system. The discrepancies between the theoretic combination of accuracy standards and empirical testing for each standard separately suggest a variety of difficulties in determining accuracy, such as statistical variability and test procedure variations. Using a chi-square test for matched samples, the discrepancies are found statistically significantly different (chi-square = 28.96, p < 0.001). Although there are fewer literature reports using the revised BHS protocol, the differences in the two systems suggest a potential need for an international agreement on accuracy determinations of blood pressure devices.

Blood Pressure Monitors↗
PubMedDate not supplied

Management of gastroesophageal reflux disease: the primary care strategy.

Gastroesophageal reflux disease (GERD) is a common problem in the community and in general practice. General practitioners and family physicians need to understand patients' reasons for consultation and also be aware of alarm symptoms suggestive of serious disease. A primary care management strategy for GERD is proposed, in which the place of endoscopic and other investigations is defined, the role of lifestyle modification discussed, and recommendations for longer-term therapy and management are made.

Algorithms↗
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Actin and actin-binding proteins in bovine spermatozoa: potential role in membrane remodeling and intracellular signaling during epididymal maturation and the acrosome reaction.

The actin cytoskeleton influences a wide range of functions in nonmuscle somatic cells, including shape, movement, and interactions with extracellular matrices. The role of actin in mammalian male germ cells, however, particularly during post-testicular development, is not well understood. In this paper, we examine 1) the distribution of 3 actin-regulatory proteins (thymosin beta10, destrin, and a testis-specific actin capping protein) involved in controlling the balance between actin monomers (G-actin) and actin filaments (F-actin), and 2) the distribution and polymerization status of actin in bull spermatozoa during epididymal maturation and following acrosomal exocytosis. Results show that in fixed, permeabilized testicular spermatozoa all 3 regulatory proteins (as determined by binding of specific antibodies) are localized primarily to the acrosomal domain but during epididymal maturation they become confined to the equatorial segment. Following ejaculation, however, they extend back into the acrosomal region. In spermatozoa induced to undergo an acrosome reaction with the calcium ionophore, A23187, further rearrangement occurs with destrin, thymosin beta10, and TS-ACP appearing in the postacrosomal domain. Actin is also found over the acrosome of testicular spermatozoa with both G- and F-actin present, although the 2 forms show slightly different patterns of distribution. Subsequently, actin in the sperm head is largely confined to the equatorial segment until F-actin appears in the postacrosomal domain of acrosome-reacted spermatozoa. This redistribution of actin and actin-regulatory proteins, coupled with changing levels of actin polymerization, suggest a continuing role for actin in both post-testicular sperm maturation and acrosomal exocytosis.

Acrosome Reaction↗
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Assistive technology to improve PC interaction for people with intention tremor.

Many patients with upper limb intention tremor encounter difficulties in mouse-driven interaction with the personal computer (PC). An assistive technology system ("the Tremor Control System"), consisting of a motion-filtering software program that supports multiple interfaces, was developed and validated with 36 persons with Multiple Sclerosis in a multi-center trial. PC-tests, requiring basic functions such as cursor placement and click and drag function, were able to differentiate between patients and control subjects (ANOVA: p<0.05). A significant time improvement on the PC-tests was found when using an optimal alternative interface instead of the standard PC-mouse (paired t-tests: p<0.01 for Point & Click test, p<0.05 for Drag & Drop test and p<0.1 for Double Click test). A significant time improvement was found for the Double Click test (paired t-tests: p<0.05) when the motion-filtering program was implemented. The number of patients able to perform fully the PC-tests increased with the Tremor Control System. Patients with marked intention tremor seemed to profit especially from this assistive technology. These users reported that working with the Tremor Control System was less fatiguing and more comfortable compared to the use of the standard PC-mouse.

Computers↗
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Connectivity: the key to point-of-care testing.

For the point-of-care testing market to grow successfully the advances in whole blood sensing technology must be accompanied by improvements in information technology to link the analytical devices to data management systems. A common connectivity standard for all instruments is being developed to replace the myriad of proprietary and incompatible solutions that currently exist.

Point-of-Care Systems↗
PubMedDate not supplied

The saline solution bag as a compensating filter.

For certain radiographic procedures, extremes in tissue composition and/or thickness can result in a poor quality image. There exists, however, a practical approach to adjust for tissue extremes by using a saline solution bag as a compensating filter. By applying this technique, radiographic image quality can be improved.

Filtration↗
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With respect to lesbians.

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Attitude of Health Personnel↗
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Bacterial tracheitis.

During a 14-month period, eight infants and children were observed with an acute, infectious, upper airway obstructive disease with features common to both croup and epiglottitis. We have termed this distinct entity "bacterial tracheitis." All patients failed to respond to treatment for croup, including racemic epinephrine delivered by intermittent positive-pressure breathing. Direct laryngoscopy consistently revealed a normal epiglottis and aryepiglottic folds but marked subglottic mucosal edema. Tracheal suctioning yielded copius mucopus below the subglottic swelling. Gram stain of this material corroborated subsequent cultures: Staphylococcus aureus, six; group A Streptococcus, one; and Haemophilus influenzae (not typed), one. All patients required periodic tracheal suctioning for relief of upper airway obstruction. Six patients required endotracheal intubation; one required a tracheostomy. Bacterial tracheitis should be considered in the differential diagnosis of a young child with a croup-like illness that is refractory to conventional therapy.

Bacterial Infections↗
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Giving patients a say.

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Group Structure↗