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Biomedical subjects

R Jaussaud

Publications and source records attributed to R Jaussaud.

29 records · Page 2Linked to original sources
PubMed1996

[Immunoprophylaxis of rabies: current recommendations].

Pre-exposure rabies vaccination should comprise 3 injections (day 0, day 7, day 28) followed by boosters 1 year later then every 5 years. Populations who are particularly exposed due to occupation, regular contact with animals in endemic areas during leisure activities or holidays should be vaccinated, especially if access to post-exposure treatment is difficult. Post-exposure treatment should comprise 5 injections (day 0, day 3, day 7, day 14, day 28) which must be given with specific immunoglobulins on day 0 if there are penetrating wounds. In persons whose prior vaccination status is well-documented and correctly maintained, post-exposure treatment may be limited to 2 injections on day 0 and day 3. The vaccine is given is intramuscular injection in the deltoid region. Immunoglobulins are used at the dose of 20 IU/kg for human immunoglobulins and at 40 IU/kg for horse immunoglobulins. The injections are infiltrated around the lesions and the remaining quantity injected in the gluteus muscle. Seroconversion must be monitored by assaying neutralizing antibodies (titre > or = 0.5 IU/ml with the RFFI Test) in vaccinated populations who regularly exposed. Monitoring can also be useful after post-exposure treatment in certain specific cases (immunosuppressed subjects, treatment protocol incorrectly or incompletely applied). An antibody titre under 0.5 IU/ml requires an immediate vaccine injection.

Guidelines as Topic↗
PubMed1996

[Granular-cell tumor: review of the literature apropos of a case of bronchial site].

Abrikossoff's tumor, also called granular cell tumor, is an uncommon condition, generally benign, which can affect every organ and specially skin and tongue. The authors report an observation of a bronchial tumor and review the literature. Possible relapse after treatment, locally or everywhere in the body, may occur as local or regional complication that may necessit heavy surgery. It appears that a benign tumor can have macroscopic and even microscopic aspect of malignancy, when real malignant tumors are extremely rare. Wide excision still remain current treatment of Abrikossoff's tumor. Endoscopic methods are an interessant and less invasive alternative to treat some deep tumors.

Adult↗
PubMed1996

The Duke criteria for diagnosing infective endocarditis are specific: analysis of 100 patients with acute fever or fever of unknown origin.

The recently proposed Duke criteria were confirmed to be more sensitive than the former Beth Israel criteria for the diagnosis of infective endocarditis (IE). To assess the specificity of the Duke criteria, we reviewed the records of 100 patients admitted to two internal medicine wards because of acute fever or fever of unknown origin (FUO). IE was considered a possible diagnosis for all patients who had had at least two blood cultures performed and one transthoracic echocardiogram obtained. The diagnosis of IE was rejected in all cases in accordance with the Duke criteria (i.e., a firm alternate diagnosis [n = 23], resolution of symptoms with no antibiotics [n = 39], or both reasons [n = 38]). To calculate the specificity of the Duke criteria, all 100 cases were then reclassified according to these criteria as if the diagnosis of IE had not been rejected. Only one patient, who probably did not have IE, was reclassified as having clinically definite IE. The specificity of the Duke criteria could therefore be calculated to 0.99 (95% confidence interval, 0.97-1). Although the design of the study may have resulted in a slight overestimation of the specificity rate, we conclude that the Duke criteria are highly specific for ruling out IE in patients with acute fever or FUO who are at low risk for IE.

Adult↗
PubMed1996

[Human periorbital dirofilariasis].

We present the case of a 72 year-old-woman with recurrent periocular inflamatory mass caused by an infection with Dirofilaria repens. The zoonotic infection is spreading by mosquito vectors from dogs to humans. Residence in endemic areas (ex-USSR, Italy, Sri Lanka, Southeastern United States) should always be suspected in patients with this type of symptomatology. The treatment is curative by the extraction of the pseudotumoral mass.

Aged↗
PubMed1995

Virulence factors (aerobactin and mucoid phenotype) in Klebsiella pneumoniae and Escherichia coli blood culture isolates.

We examined the presence of two virulence factors in 241 blood isolates of Klebsiella pneumoniae from patients hospitalized during 1989 and 1990 in 7 French hospitals, and 125 blood isolates of Escherichia coli from one hospital. Aerobactin was scored phenotypically and genotypically with an intragenic DNA probe of 2 kb. The mucoid phenotype was assessed by culture on trypticase soy agar and by genotypic analysis (intragenic DNA probe of 235 bp). Only 6% K. pneumoniae isolates were aerobactin-positive with no significant variation according to geographical location while 20% of K. pneumoniae isolates displayed the mucoid phenotype, with a significant variation according to hospital. Aerobactin was always associated with the mucoid phenotype. The frequency of aerobactin production but not mucoid phenotype (14%) was higher among E. coli isolates (48%). They harbored two types of large plasmids. Intraperitoneal injection into mice of 10(3) cfu of K. pneumoniae producing both virulence factors demonstrated that capsular serotype K2 was the more virulent K23 and K28.

Animals↗
PubMed1995

[Mycotic aneurysm of the posterior tibial artery and pseudo-phlebitis: contribution of color Doppler ultrasonography].

Mycotic aneurysm of the posterior tibial artery and pseudophlebitis: role of color Doppler sonography A case of a 78-year-old male patient presenting with endocarditis caused by Streptococcus bovis and pseudophlebitis of the left lower limb is described. Color Doppler sonography ruled out thrombophlebitis and showed a large pulsatile mass of the posterior compartment of the leg due to a mycotic aneurysm of the posterior tibial artery. This aneurysm was confirmed by angiography and treated by surgery. The important role of color Doppler sonography for the diagnosis of this particular case is emphasized.

Aged↗
PubMed1994

Rapid and simple cannulation technique for repeated sampling of cerebrospinal fluid in the conscious rabbit.

A cannulation technique for continuous sampling of cerebrospinal fluid in unanesthetized freely moving rabbits was established. A permanent Teflon catheter constructed easily and inexpensively from commercially available material was placed into the cisterna magna and fixed to the skull by anchoring screws and dental cement. The surgical procedure required a minimum of time and induced minimal trauma, allowing studies in which physiologic conditions are required. The Teflon catheter induced minimal foreign body reaction, the system had minimal dead volume, and its size was small enough to allow the simultaneous implantation of other devices.

Animals↗