Limitation of computerized averaging of ECG during stress testing.
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Biomedical subjects
Publications and source records attributed to R Jain.
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Seventy-two out of 656 patients treated by coronary stenting between January 1995 to May 1997 underwent elective multivessel stenting as a strategy for nonsurgical revascularization in patients with two-vessel (n = 37) and three-vessel (n = 35) disease. Their age ranged from 35 to 77 years (mean: 53.6 +/- 9.2) and the majority (77.8%) were males. The patients were included if the target vessel was more than 2.7 mm in diameter and subserved a moderate to large area of viable myocardium, provided the target lesion was considered approachable by stent. In all, 160 stents were deployed in 146 vessels with a mean of 2.2 stents per patient. The procedure was performed on all the target lesions in one stage in 51(70.8%) and two stages in 21(29.2%) patients. Two-vessel stenting was done in all except 2 patients who received stents in all the three major arteries. Successful deployment of the stent was achieved at the target site in all patients without any major in-hospital complications including subacute stent thrombosis, myocardial infarction (MI), emergency bypass graft surgery (CABG) or death. Clinical follow-up was available in 66(91.6%) patients at a mean of 7.8 +/- 5.5 months. The actuarial survival rates were 98.6, 96.7 and 94.6 percent, respectively at one, 3 and 6 to 12 months after the procedure with an event-free survival (absence of death, MI, recurrence of angina or any revascularization) of 98.5 percent at one, 93 percent at 3, 83.2 percent at 6 and 68.4 percent at 12 months. Only 15(22.7%) patients developed any event and target lesion revascularization was required in 8(12%) patients. In conclusion, multivessel stenting in patients with two- and three-vessel coronary disease is feasible, safe and effective in preventing major in-hospital complications as well as reducing the recurrence of clinical events and need for revascularization on follow-up.
Benign cystic mesothelioma of the peritoneum is uncommon and usually occurs in women. We report this condition in a man, who was treated successfully by surgical excision of the tumor.
The argyrophilic technique for staining proteins associated with nucleolar organizer regions (AgNOR's) was applied to 32 liver biopsy specimens. These included 10 normal livers, 10 cirrhosis, 10 hepatocellular carcinomas (HCC) and 2 cholangiocarcinomas. The range of the mean number of NORs per nucleus was 1.3-1.7 (95% CI: 1.4-1.6) for normal liver, 2.4-3.5 (2.8-3.2) for cirrhosis, 3.0-7.9 (3.7-5.6) for HCC and 4.0-4.2 (3.9-4.3) for cholangiocarcinoma. The difference observed was statistically significant. The AgNORs were small and discrete in normal and cirrhotic liver and relatively larger and scattered in distribution in HCC. These results indicate that both quantitative and qualitative analysis of AgNORs may be useful as an adjunct to routine haematoxylin and eosin stain to distinguish cirrhosis from HCC especially when the latter is well differentiated.