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R J Sutherland

Publications and source records attributed to R J Sutherland.

76 records · Page 5Linked to original sources
PubMedDate not supplied

Blood coagulation parameters in clinically normal intensively farmed red deer (Cervus elaphus) and fallow deer (Dama dama).

Reference ranges for five parameters of blood coagulation were established in clinically normal farmed fallow deer (Dama dama) and red deer (Cervus elaphus). Storage of plasma at -15 degrees C resulted in small increases in activated partial thromboplastin time (APTT) for both species, and in the one stage prothrombin time (OSPT) of fallow deer, between days 1 and 30. These times were then stable between days 30 and 60. The fibrinogen levels of fallow deer plasma showed a small apparent increase over 60 days. These storage artefacts were not of sufficient magnitude to preclude the use of such plasma for diagnostic purposes although they could limit its use in research. Levels of fibrin/fibrinogen degradation products (FDP) were not affected by storage at -15 degrees C. Rabbit brain thromboplastin appeared adequate for OSPT determination in both species. The activated clotting time (ACT) is recommended as a field test for screening the intrinsic and common pathways of blood coagulation in deer.

Journal Article↗
PubMedDate not supplied

Dissociation of the medial prefrontal, posterior parietal, and posterior temporal cortex for spatial navigation and recognition memory in the rat.

Rats with lesions of the medial prefrontal, posterior parietal, or posterior temporal cortex were tested in five spatial navigation tasks, which varied in egocentric or allocentric demands, a visual discrimination task, and two delayed nonmatching-to-sample tasks. Rats with prefrontal lesions were impaired at every spatial navigation task, whereas rats with posterior parietal lesions had selective spatial navigation impairments. Rats with prefrontal lesions were also impaired at a visual delayed nonmatching-to-sample task, as they were unable to learn the task, even with no delay. The results are consistent with the idea that the basic plan of mammalian cortex includes prefrontal, posterior parietal, and posterior temporal regions, each of which have generally similar functions across mammalian taxa. There are, however, species-typical differences that reflect specific ecological pressures on the development of the different regions.

Animals↗