Low power histopathologic tissue projection.
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Biomedical subjects
Publications and source records attributed to R J Stock.
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Three cases of tubal patency following Uchida-type tubal ligation were identified. A histopathologic study of the excised segments in question revealed incomplete transecton of the tube. Modification of the Uchida procedure by attempting to remove a small segment of tube led to simple unroofing of the fallopian tube. This procedural defect was suspected by the presence of incomplete lumens in the tubal segments initially submitted to pathology. The author stresses the importance of proper exchange of information between the surgeon and pathologist to avoid tubal ligation failures that could be identified and otherwise prevented.
Forty-nine cases of ovarian endometrioid carcinoma with squamous foci were reviewed. Of particular interest was the biologic behavior of the neoplasms in relation to the appearance of the epithelium. As previously noted for the analogous uterine endometrial tumors, the ovarian adenosquamous lesions occurred later in life, were more advanced, were associated with less differentiated adenocarcinomatous components, and had a poorer prognosis. The five-year survival rate for patients with adenosquamous endometrioid ovarian carcinoma was 21% in comparison with the 90% survival found in patients with ovarian endometrioid adenocanthoma.
The difficulties encountered in establishing a diagnosis of a malignant peritoneal mesothelioma are emphasized in a patient who developed the lesion 16 years after radiation therapy for a seminoma of the testis. Historically, histologically, electron microscopically, and by microincineration, there was no evidence of asbestos exposure. We believe that present lesion may be a consequence of prior radiation therapy.
The etiology of annular constrictions and/or intrauterine amputations is believed to be the result of an embryologic developmental defect or of a happenstance mechanical constriction. Evidence drawn from 3 infants and 1 fetus is used to evaluate the above theories. It is concluded that simple mechanical constriction is most likely not the etiology, and that a focal degenerative process is operative, which is consistent with the changes originally described by Streeter. In view of present embryologic concepts, this lesion is not a primary embryologic defect as postulated by Streeter, but a secondary superimposed disease process of unknown etiology.
Five cases of squamous cell carcinoma of the cervix associated with widespread squamous cell carcinoma in situ of the endometrial surface are reported. In one case, carcinoma in situ was also found in one fallopian tube in continuity with the cervicoendometrial lesion. A survey of the literature reveals only 20 cases with similar surface endometrial involvement by cervical squamous cell carcinoma. Of these, the fallopian tubes were involved by an identical lesion in six cases only. Pyometra and cervical stenosis were reported in about 66% of the cases. This rare form of upward cervical cancer extension was present in five of 680 cases (0.7%) of squamous cell carcinoma of the cervix in the file of the Tumor Registry of Magee-Womens Hospital.
An evaluation was made of 268 patients undergoing elective sterilization with respect to the ensuing development of menorrhagia, pelvic pain, and the need for gynecologic surgery. Preoperative and follow-up postoperative questionnaires of patients undergoing laparoscopic sterilization were compared, and additional data were drawn from clinical records and operative reports to substantiate real changes. A study of the cases puts the incidence of menorrhagia at 6%, pelvic pain at 6%, and necessary subsequent gynecologic surgery at 4%.
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A 27-year-old woman, gravida 2, para 2, who presented with a 5-year history of dysfunctional uterine bleeding following a terminated pregnancy is described. Hysterosalpingography suggested a loss of muscle tone and a mass. Pathologic examination revealed a prominent vascular system consistent with diffuse lymphangiectasia.
The efficacy of prehysterectomy curettage in ruling out an endometrial cancer was evaluated in three ways. First, by an evaluation of the extent of routine prehysterectomy curettage; second, by the assessment of the clinicians' ability to recognize endometrial cancer on the basis of curettings; and third, by evaluating the presence of a gross endometrial lesion in those uteri removed without a preoperative diagnosis of an endometrial malignancy. It was concluded that the examination of the opened excised uterus was more valuable than prehysterectomy curettage for the operative diagnosis of an endometrial malignancy.
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The wooden Ayre spatula with an extended endocervical tip was compared with both designs of the plastic Accu-Pap sampler in two series of 100 consecutive patients to compare their adequacy in obtaining samples for cervical cytology. There was no significant advantage noted in the smears taken by either spatula. In terms of the sequence of smears, the second smear generally contained more endocervical cells and less often showed an absence of diagnostic cells.