Nicotinamide adenine dinucleotide splitting enzyme: a plasma membrane protein of murine macrophages.
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Animals↗
Biomedical subjects
R J Seeley
Publications and source records attributed to R J Seeley.
Nicotinamide adenine dinucleotide-splitting enzyme in normal, elicited and activated peritoneal macrophages of the mouse.
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Acid Phosphatase↗
Nicotinamide adenine dinucleotide splitting enzyme: a characteristic of the mouse macrophage.
Murine macrophages are endowed with nicotinamide adenine dinucleotide splitting activity that is markedly higher than that of other cells, tissues, or organs of the mouse. This enzyme therefore can be used as a biochemical marker for distinguishing macrophages from other cells of the lymphoreticular system and from polymorphonuclear leukocytes.
Animals↗
Inheritance and longevity of infectious pancreatic necrosis virus in the zebra fish, Brachydanio rerio (Hamilton-Buchanan).
Zebra fish (Brachydanio rerio) were injected with infectious pancreatic necrosis virus (IPNV) and then spawned to determine whether the virus was passed on to the eggs, and if it was, how long it remained in the free-swimming F1. The mating variations included parents receiving one or two injections of virus, and within these categories, matings in which both parents were treated or only one parent was treated. The results showed that transmission of IPNV to the egg did occur, and that this transmission was via the female alone. However, if the female was allowed to produce antibodies to the virus, as when she received two injections of IPNV, she transmitted the virus to the eggs for only a short period of time. In addition, when the virus was transmitted to the egg, it remained in the free-swimming F1 for a period of at least 5 months.
Animals↗
The effect of crowding on the immune response of the blue gourami, Trichogaster trichopterus, to infectious pancreatic necrosis (IPN) virus.
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Ammonia↗
The role of the hypothalamic melanocortin system in behavioral appetitive processes.
Much evidence suggests that the hypothalamic melanocortin (MC) system plays an important role in the control of food intake. However, investigations of the potential behavioral mechanisms have been limited to measures of aversion. The purpose of the present experiment was to assess whether other behavioral consequences of administration of MC peptides were similar to those produced by 0- or 24-h food deprivation, respectively. Rats were first trained while food deprived that a tone predicted the delivery of peanut oil. They then received exposure to oil under food deprivation, satiation, intra-third-cerebroventricular (i3vt) infusion of MTII (a potent MC agonist) or SHU-9119 (a potent MC antagonist). All rats were then tested during extinction for levels of responding to the tone under food satiation. Previous results demonstrated that sated exposure reduces subsequent test responding to the tone. During the present extinction test, rats that received sated exposure exhibited reduced responding to the tone, relative to rats that received deprived exposure. Unlike satiation, rats that received exposure after MTII exhibited continued high levels of responding to the tone. Further, rats that received SHU-9119 exhibited a small reduction in responding. These data suggest that MTII and SHU-9119 do not influence intake via the same mechanisms as hunger and food satiation, respectively.
Animals↗