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Biomedical subjects

R J Reed

Publications and source records attributed to R J Reed.

At least 73 records · Page 4Linked to original sources
PubMed1982

Monophasic, glandular, synovial sarcomas and carcinomas of the soft tissues.

In soft tissues, malignant tumors with epithelial qualities are usually metastatic carcinomas. A rare, primary, soft-tissue tumor that is uniformly carcinoma-like is the monophasic, glandular, synovial sarcoma. We studied three cases of carcinoma-like neoplasms of soft tissue. In one primary tumor and two recurrent tumors of soft tissue, the histologic patterns were uniformly glandular. For the two recurrent tumors, the primary lesions were a classic, synovial sarcoma and a biphasic, synovial sarcoma with a histiocytic, stromal component. By inference, the third tumor, a primary "carcinoma" of soft tissue, may represent a de novo, monophasic, glandular, synovial sarcoma. Synovial sarcoma should be considered in the differential diagnosis of carcinoma like tumors discovered in the soft tissues.

Adult↗
PubMed1980

Treatment of lentigo maligna and lentigo maligna melanoma.

Thirty-eight cases of lentigo maligna and 22 cases of lentigo maligna melanoma, were reviewed in order to compare cure rates of various methods of treatment. Surgical excision resulted in the best cure rate (91%); destructive modalities were less successful (45%). All lesions treated with 5% 5-fluorouracil recurred.

Adult↗
PubMed1980

Granular cell tumor.

The case report presented herein involves a granular cell tumor of the vulva, an uncommon site, with unusual clinical characteristics.

Adult↗
PubMed1980

Nevi, lentigines, and melanomas in blacks.

Two hundred fifty-one black patients were examined for the presence of melanocytic nevi. The average number detected was 8.3 per patient. Light-skinned blacks had a greater number of total body nevi, while dark-skinned blacks had more lesions on the palms and soles. The usual histologic pattern seen in plantar-palmar lesions was that of lentigo simplex. The differentiation of lentigines of the palms and soles from early expression of acral lentiginous melanomas may be difficult; however, most acral pigmented lesions do not require excision.

Adult↗
PubMed1980

Acral lentiginous melanoma.

Acral lentiginous melanoma represents a fourth variant of malignant melanoma in company with lentigo maligna melanoma, superficial spreading melanoma, and nodular melanoma. It is characterized by a lentiginous (radial) growth phase that evolves over months or years to a dermal (vertical) invasive stage. Clinical and pathologic features were reviewed in 35 cases of acral lentiginous melanoma of the palms and soles. This variant of melanoma probably represents the most common expression of melanoma in blacks; two thirds of the patients in our study were black. The average three-year survival rate was 11%.

Adult↗
PubMed1979

Neurotropic melanoma. A variant of desmoplastic melanoma.

We report a group of neuroid, cutaneous tumors that are usually associated with, or preceded by a melanocytic dysplasia. For this clinicopathologic entity we have chosen the term neurotropic melanoma. The neurotropic melanoma is a cutaneous fibrous tumor whose clinical course is characterized by local infiltration, multiple recurrences, and commonly by metastases. Its microscopic picture is characterized by atypical "neuroma-like" patterns, by poorly defined margins, and by neurotropism. Its early or precursory melanocytic dysplasias include lentigo maligna (actinic or lentigo maligna variant), and a melanoma with borderline cytologic characteristics (minimal deviation variant). A third type is not preceded by a recognizable melanocytic dysplasia: it has "neuroma-like" qualities at its inception (de novo variant). In our 22 cases, the preponderant sites were the head, neck, and lip. The patients were fair-faced, and 18 of the patients were over 40 years old. Seventeen patients had one or more recurrences. Of 16 patients with follow-up, nine died with evidence of disease, five are alive with active disease, and seven are apparently free of disease.

Adult↗
PubMed1979

Periumbilical perforating pseudoxanthoma elasticum.

Periumbilical pseudoxanthoma elasticum (PXE) with transepidermal elimination of altered elastica presented a distinctive clinical pattern in six middle-aged, multiparous women. Other sites usually affected in PXE were spared. The possible genetic predisposition to PXE of these patients found its expression in the periumbilical skin, a site exposed to the trauma of multiple pregnancies. The extruded elastica had tinctorial properties that were characteristic of PXE. The clinical picture in our cases differs from clasic PXE. A peculiar acquired cutaneous PXE is not excluded.

Female↗
PubMed1978

Trace metals in some fish species of South Carolina.

Samples of fish from freshwater and saltwater sources of ocean, rivers, and lakes over the state of South Carolina were collected. The fish collected were Shrimp, Silver Snapper, White Bass, Catfish, Mudfish and Trout. The sample flasks were incubated in a constant temperature stirring water bath at 58 degrees C until clear solution in reagent-grade nitric acid. Triplicate samples of fish muscle tissue were analyzed by wet digestion and dry digestion methods. Trace metal levels were determined by flame atomic absorption using a Perkin-Elmer Model 306 spectrophotometer. Mercury determination was made by Coleman MAS-50 mercury analyzer. A significant finding of this report is that saltwater fish have more trace metal levels than freshwater fish, and larger fish have higher trace metals than smaller fish. Iron and zinc levels were much higher in Shrimp than any other species analyzed.

Animals↗
PubMed1978

Penetrating wounds of the neck and upper thorax.

During the past decade, a method utilizing individual case assessment has been employed in the treatment of 51 patients with penetrating wounds of the neck and upper thorax. Only those wounds penetrating the platysma are included. Thirty-five patients (68.6%) underwent neck exploration; 16 patients (31.4%) were managed nonoperatively. Overall, five patients died, four patients following operative treatment and one treated nonoperatively, for a mortality rate of 9.8%. In the nonoperative group, a mortality of 6.2% (one death) compares favorably with an operative mortality of 11.4% (four deaths). Ten patients (29%) in the neck exploration group exhibited significant later morbidity compared to seven patients (44%) in the patients not explored. Therefore the morbidity from a negative neck exploration was only 2% (one of 20 patients). The techniques for exploring the neck are discussed. Adequate surgical exposure is largely dependent on the possibility of vascular injury, the most common cause of death in this series.

Adult↗