ECMO accidents: a survey of the incidence of mechanical failure and user error during extracorporeal membrane oxygenation.
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Data Collection↗
Biomedical subjects
R J Powers
Publications and source records attributed to R J Powers.
Adrenal calcification and congenital nephrotic syndrome in three American Indians.
Two Pima and one Papago Indian infants with congenital nephrosis and adrenal calcifications are described. All developed anasarca early and none had an explanation for the adrenal calcification.
Adrenal Gland Diseases↗
Atypical endogenous opioid systems in mice in relation to an auto-addiction opioid model of anorexia nervosa.
We have proposed that the atypical opioid system in the mouse may be representative of that in the anorexia nervosa patient and may account for a biological predisposition to the disorder. This is in the context of our auto-addiction model of anorexia nervosa in which endogenous opioids play a critical role in its etiology. Morphine activation of the endogenous opioid systems increases food intake and causes sedation in most species, including normal humans and rats. In contrast in BALB/C mice, morphine causes anorexia and hyperactivity, which we suggest may be true in the anorexia nervosa patient. A variety of atypical opioid systems have been demonstrated in different mouse strains, based on other responses. The present study examines these strains with reference to the responses relevant to our anorexia nervosa model. Three patterns are described--anorexia with hyperactivity (BALB/C and C57BL/6J mice), anorexia without hyperactivity (DBA/J mice), and a biphasic curve with hyperphagia at low doses and anorexia and hyperactivity at higher doses (CF-1 mice). Only female mice were used. These atypical opioid systems may reflect a spectrum of biological predispositions to the disorder. These strain differences may also provide useful correlations of the genetic determinants of various opiate responses and provide useful comparisons in characterizing the essential features responsible for the atypical responses.
Animals↗
ECG lead placement and configuration.
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Critical Care↗
Hepatitis B virus. Inappropriate reactions to transmission risks.
Ten patients designated as hepatitis B surface antigen (HBsAg) carriers were screened for inappropriate reactions to their disease. Assessment with a 32-item questionnaire showed three carriers to have underreacted to the risks of HBsAg transmission through misunderstandings or denial concerning the disease. One carrier, through severe social withdrawal, showed overreaction to the possibilities of disease transmission. Counseling was provided regarding the risks of HBsAg transmission. At a one-month follow-up, all carriers appeared appropriately aware of the risks of transmission, and one of two carriers referred for psychotherapy showed greatly improved social adjustment. We recommend that persons treating HBsAg carriers screen routinely for inappropriate reactions to risks of disease transmission and provide counseling as needed.
Carrier State↗
Pb encephalopathy mimicking Reye syndrome.
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Adult↗