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Biomedical subjects

R J Lull

Publications and source records attributed to R J Lull.

31 records · Page 2Linked to original sources
PubMed1980

Radionuclide imaging in the assessment of lung injury.

Nuclear medicine imaging techniques are being more widely applied to study a variety of lung injuries. Ventilation and perfusion imaging is often superior to other roentgenographic techniques for establishing the diagnosis and demonstrating the extent of such injuries. At several large burn centers, the Xe-133 washout technique has become the cornerstone for diagnosing early inhalation injury. The overall accuracy of this procedure is 92%. Regional decreases in ventilation and perfusion can reliably localize aspirated radiolucent foreign bodies. Disproportionate perfusion changes are often the earliest indicator of radiation pneumonitis and other forms of vascular injury. Other types of injury, such as gastropulmonary aspiration, blunt trauma, and near-drowning, require further evaluation before the ultimate role of nuclear imaging is defined. An imaging technique to assess capillary permeability in the adult respiratory distress syndrome would be of great clinical benefits.

Blast Injuries↗
PubMed1980

Hepatoma visualization with Tc-99m pyridoxylidene glutamate.

Tc-99m sulfur colloid is concentrated in Kupffer cells of the liver, whereas the new biliary agents are processed by hepatic parenchymal cells. A case of primary hepatocellular carcinoma, appearing as a defect on sulfur-colloid liver scan and visualized on a biliary scan, is presented. The possible role of biliary scanning in the evaluation of a defect on sulfur-colloid liver scan is discussed.

Aged↗
PubMed1977

The use of steroids in inhalation injury.

Steroids exert no beneficial effect upon acute pulmonary dysfunction created by nitrogen tetroxide inhalation and may worsen small airway obstruction in the early phases of injury. Treatment, therefore, is still largely symptomatic and supportive.

Animals↗
PubMed1976

Use of 133xenon in early diagnosis of inhalation injury.

133Xenon lung scanning post-thermal injury was used to detect inhalation injury in 86 patients admitted to the United States Army Institute of Surgical Research during 1974. Inhalation injury was indicated by the 37 (43%) positive scans. Based on all available clinicopathologic evidence, 11 (13%) of the scans were erroneous with seven (8%) falsely positive and four (5%) falsely negative. Eighty-six per cent of the scans were "appropriate." Addition of bronchoscopy and/or pulmonary function testing appeared to improve diagnostic accuracy. By using any pair of tests, falsely negative diagnoses were virtually eliminated. Inhalation injury, as expected, had an adverse effect on survival rates. The group of patients whose expected mortality lay between 40 and 59% were most notably affected. One hundred per cent (five of five) of those with inhalation injury died; only one of eight without inhalation injury died.

Bronchoscopy↗
PubMed1976

Bronchial adenoma causing unilateral absence of pulmonary perfusion.

This case of bronchial adenoma is used as a clinical model demonstrating absence of pulmonary perfusion by 131I-MAA scanning secondary to bronchial obstruction. Radiographic and radionuclide studies are correlated and other causes of pulmonary hypoperfusion discussed. The literature and related cases are reviewed.

Adenoma↗