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R J Kahn

Publications and source records attributed to R J Kahn.

103 records · Page 6Linked to original sources
PubMedDate not supplied

Tricyclic treatment of generalized anxiety disorder.

While tricyclic antidepressants (TCAs) have now long been used in treatment for depressive and panic-phobic disorders, we reviewed and reported on their efficacy in generalized anxiety states. These ill-defined states usually have admixtures of anxiety and depression. While there is no neat diagnostic categorization to fit this wasteland of yet-to-be-defined disorders, they show surprising responsiveness to imipramine. The onset of efficacy appears to begin at about 2 weeks or later and is probably superior to at least one well-known benzodiazepine, chlordiazepoxide, well beyond that time. It is not possible to dismiss these observed antianxiety effects as secondary to antidepressant effects or as attributable to the unintended inclusion of a peculiarly sensitive subset of individuals such as panic-phobic patients. These findings indicate that affect regulation by TCAs applies to so-called generalized anxiety as well as to depression and panic-phobic disorder. Brief reminders and guidelines are outlined for the possible clinical use of TCAs in anxiety disorders, but there remain more questions than answers. Several replication studies concerning the results reviewed here are now under way.

Antidepressive Agents, Tricyclic↗
PubMedDate not supplied

[Acute renal insufficiency in surgery: the surgeon's role].

The surgeon has an active role to play in the treatment of acute renal failure (ARF) occurring in surgical patients. Surgical complications are very often the cause of ARF and their treatment is the only way to cure uremia.

Acute Kidney Injury↗
PubMedDate not supplied

Quality and duration of life for old people.

The evolutions of the medical art, of the medical ethics and of the society create a new concept: the quality of life. The well-being of the patients has to be determined by the patients themselves but some general rules have been found essentially for the old patient.

Aged↗