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Biomedical subjects

R J Isaacson

Publications and source records attributed to R J Isaacson.

At least 55 records · Page 3Linked to original sources

Biotechnical and other factors affecting orthognathic surgery.

Orthognathic surgery is a rapidly growing biotechnologic interaction involving alterations of facial form and dental occlusion. This article describes some of the important and complex psychological, sociological, ethical, and public policy issues involved. Advances in the latter issues are necessary for advancement of the field.

Adolescent↗

The morphology of canines in relation to preadjusted appliances.

The canine occupies the transition from anterior to posterior occlusion. Following orthodontic treatment the canine's incisal edge occlusion demonstrates the tip and torque present in the appliance that was used. The effective torque of the bracket, however, is influenced by the tooth morphology at the bracket's base. The morphology of the facial surface can be described by an angle formed between the tangent at the point of bracket placement and the long axis of the crown. In this study, tangent angles at four millimeters and five millimeters from the cusp tip of 100 maxillary and 70 mandibular canines were determined. There was a significant difference between tangent angles at the same location on different canine teeth and also at different locations on the same canine tooth. Proximal collum angles were also measured in this study and there was a significant negative proximal collum angle in maxillary canines and a significant positive proximal collum angle in mandibular canines. The presence of these normal biologic variables will either enhance or minimize the torque supplied by preadjusted appliances, depending on a combination of prescription used and biologic variable present.

Cuspid↗

Three biologic variables modifying faciolingual tooth angulation by straight-wire appliances.

The facial surface contours of 600 maxillary and mandibular teeth, including 50 of each type of tooth from central incisors to first molars, were measured. Facial contours present at the same location, facial contours from occlusal/incisal to gingival surfaces and the angle formed by the coronal and radicular long axes varied among teeth of the same type. The magnitude of the variation found was so great as to suggest that differences between patients or differences in height of bracket placement are greater than the differences between the standard torque prescriptions now used in orthodontics. No single point, including the coronal midpoint (LA point), was found to be constant among teeth of the same type. Variation in facial surface contour tended to be greater in the posterior teeth than in the anterior teeth. Future custom construction of brackets, adjusted to individual facial contour differences, will also require information regarding optimal tooth position in the head, including compensations necessary for variations in facial skeletal pattern.

Humans↗

Superimpositional assessment of treatment-associated changes in the temporomandibular joint and the mandibular symphysis.

This article analyzes differences in the measured displacement of the condyle and of progonion when different vectors of force are delivered to the maxilla in the course of non-full-banded, Phase 1, mixed-dentition treatment for the correction of Class II malocclusion. The 238-case sample is identical to that for which changes in other parameters of facial form have been reported previously. Relative to superimposition on anterior cranial base and measured in a Frankfort-plane-determined coordinate system, we have attempted to identify and quantitate (1) the displacement of each structure which results from local remodeling and (2) the displacement of each structure which occurs as a secondary consequence of changes in other regions of the skull. We have also attempted to isolate treatment effects from those attributable to spontaneous growth and development. At the condyle, we note that in all three treatment groups and in the control group there is a small but real downward and backward displacement of the glenoid fossa. This change is not treatment induced but, rather, is associated with spontaneous growth and development. (See Fig. 5.) Some interesting differences in pattern of "growth at the condyle" were noted between samples. In the intraoral (modified activator) sample, there were small but statistically significant increases in growth rate as compared to the untreated group of Class II controls. To our surprise, similar statistically significant increases over the growth rate of the control group were noted in the cervical sample. (See Table III, variables 17 and 18.) Small but statistically significant differences between treatments were also noted in the patterns of change at pogonion. As compared to the untreated control group, the rate of total displacement in the modified activator group was significantly greater in the forward direction, while the rate of total displacement in the cervical group was significantly greater in the downward direction. There were no statistically significant differences in the rate of total displacement of pogonion between the high-pull sample and the control sample. (See Table IV, variables 21 and 22.

Activator Appliances↗

Quantitative analysis of the orthodontic and orthopedic effects of maxillary traction.

This article analyzes differences in displacement of ANS and of the upper first molar when different vectors of force are delivered to the maxilla in non-full-banded Phase I mixed-dentition treatment of Class II malocclusion. The sample is identical to that for which we have previously reported differences in change in several key measures of mandibular and facial shape. It includes a cervical-traction group, a high-pull-to-upper-molar group, a modified-activator group, and an untreated Class II control group. Using newly developed computer-conducted procedures, which are described, we have been able to partition the orthodontic and orthopedic components of upper molar displacement and also to isolate treatment effects from those attributable to spontaneous growth and development. In the region of ANS, small but statistically significant and clinically meaningful differences were noted between treatments. When the intercurrent effects of growth and development had been factored out (Table III), orthopedic distal displacement of ANS was significantly greater in the high-pull and cervical groups than in the activator group. Orthopedic downward displacement of ANS was seen to be significantly greater in the cervical group than in the high-pull and activator groups. In the region of the first molar cusp, mean distal displacement of the tooth as an orthopedic effect was found to be almost identical in the cervical and high-pull groups (although variability was greater in the cervical group), but the mean orthodontic effect was significantly greater in the high-pull group than in the cervical group. In the cervical group, where relatively light forces were used for relatively long treatment periods on average, more of the total distal displacement of the upper molar was of an orthopedic character than of an orthodontic character. Conversely, in the high-pull group, in which relatively heavier forces tended to be used for briefer treatment periods, most of the distal displacement at the upper molar was of an orthodontic character. These observations are contrary to expectations from conventional orthodontic theory. In the activator-treated group, roughly equal components of the treatment-associated distal displacement of the upper molar were of the orthodontic and orthopedic types. As concerns changes in the vertical direction in the region of the molar cusp, significant intrusion of both the orthopedic and orthodontic types was seen in the high-pull sample as compared to each of the other groups examined.(ABSTRACT TRUNCATED AT 400 WORDS)

Activator Appliances↗

Growth contributions to class II corrections based on models of mandibular morphology.

Various morphologies of human models are modeled with various growth patterns to demonstrate the role of mandibular morphology on growth contributions to Class II corrections. Growth patterns are described by centers of mandibular rotation relative to the cranial base. Centers of rotation are used to determine several parameters of growth generated by a computer programmed to show growth effects. The direction and amount of condylar growth are held constant. With condylar growth constant, various centers of rotation of the mandible reveal that maximum Class II molar correction is present when the condyle is vertically located farthest from the molar. Of lesser importance, Class II corrections are greater when the condyle is anteroposteriorly closest to the molar.

History, 18th Century↗

Mechanics, growth, and class II corrections.

Growth of the orofacial region is quantitatively described by locating the center of mandibular rotation relative to the cranial base. The center of mandibular rotation is positioned by the ratio of vertical facial growth (AFH/PFH) and the direction of condylar growth. Appliance therapy is associated with changes in the means of both of these parameters. These changes reduce or stop favorable anterior mandibular rotation and redirect the mean condylar growth vector more posteriorly. When appliance therapy is stopped, these parameters return toward their resting values. The mean direction of the condylar growth vector became even more anteriorly directed after treatment than the pretreatment mean value. These data support the hypothesis that orthodontic appliances significantly alter the facial growth pattern and when they are stopped, the growth pattern tends to rebound to or beyond the pretreatment values.

Activator Appliances↗

Movement of the proximal and distal segments after mandibular ramus osteotomies.

Data was collected from 27 patients who were treated with various ramal surgical procedures. Movements of the proximal segment during and after surgery were frequently noted. If the proximal segment was moved from its preoperative position and fixed to the distal segment, occlusal relapse was visible shortly after release of maxillomandibular fixation. Proximal segments displaced during surgery and not fixed to the distal segment frequently returned to their preoperative positions during fixation or assumed positions of biologic equilibrium. In such cases, occlusal relapse was minimal or nonexistent.

Adolescent↗

Differential treatment planning for mandibular prognathism.

The treatment records of thirty-eight cases of mandibular prognathism treated by orthodontics means only (ORTHO) were evaluated. The pretreatment records of twenty cases of mandibular subapical esteotomy (SUB) and twenty cases of mandibular setback (SET) were evaluated for comparison and contrast with the pretreatment ORTHO records and with each other. Dental, skeletal, and soft-tissue parameters in the vertical and horizontal planes of space were recorded. Statistical analysis of means of parameters of the pretreatment records provided documentation of the discriminant variables in each of the following paired groups: ORTHO-SUB, ORTHO-SET, and SUB-SET. Analysis of the data as indicated above led to the following conclusions: 1. Three discriminant groups of mandibular prognathism of various degrees of severity were discernible when comparisons of treatment categories simulating clinical decisions were made. The ORTHO group was distinguished from the SUB group in the horizontal plane and, more strongly, in the vertical plane. The ORTHO group was distinguished from the SET group in the vertical plane and, more strongly, in the horizontal plane. The SUB group was distinguished from the SET group in the horizontal plane. 2. The physiologic developmental status of the patient should be carefully evaluated. 3. Anteroposterior dysplasias should be assessed relative to the cant of the mandibular plane. True denture base discrepancies can be noted relative to the occlusal plane. 4. Documentation of vertical dysplasias should include measurements of craniofacial divergence (SN-MP, FH-MP, and OP-MP). 5. In assessing the profile evaluation of the patient with mandibular prognathism, particular attention should be focused on facial contour angle (FCA), nasolabial angle (NLA), and relative lower lip protrusion (LLP). 6. Any numerical values obtained in the evaluation of the dental, skeletal, or soft-tissue characteristics of mandibular prognathism should be considered only as descriptive, diagnostic guides and not as components of a diagnostic formula.

Alveolar Process↗

Tooth-size discrepancy in mandibular prognathism.

A Bolton analysis of seventy-eight cases of Angle Class III malocclusion, twenty-six cases of Angle Class I malocclusion, and twenty-six cases of Angle Class II malocclusion was recorded. Frequency of excess mandibular tooth structure, magnitude of the excess, over-all ratios, and anterior segment ratios were computed and analyzed. Two clinical cases were presented to show the advantage of tooth-size harmony in mandibular prognathism. Analysis of the data as presented above suggests the following conclusions: 1. The frequency of mandibular tooth-size excess (over-all ratio) in this sample was greater in cases of mandibular prognathism than in Angle Class I and Angle Class II cases. 2. In those cases with mandibular tooth-size excess, there was a suggestion that the magnitude of the excess was greater in cases of mandibular prognathism than in Angle Class I and Angle Class II cases. 3. A tooth-size discrepancy analysis should be included as one part of the diagnostic records for mandibular prognathism.

Adolescent↗

The role of dental compensations in the orthodontic treatment of mandibular prognathism.

Thirty-six patients with orthodontically treated mandibular prognathism were recalled for cephalometric and clinical evaluation. A comparison group of 32 non-Class III patients was similarly examined. Analysis of variables associated with the anterior dentition and documentationtion of labial gingival recession and tooth mobility led to the following conclusions concerning the role of dental compensations in the orthodontic treatment of mandibular prognathism. 1. Vertical and horizontal dental compensations were quantitated in the dentition of the study group (pretreatment to postretention). 2. Increased labial gingival recession and increased tooth mobility in functional jaw positions were present in anterior maxillary and mandibular teeth of the study group relative to the comparison group. 3. Proper diagnosis and the establishment of realistic treatment objectives by clinician and patient are necessary to avoid undesirable sequelae and/or undesirable facial esthetics in the treatment of mandibular prognathism.

Humans↗

Measurement of tooth movement.

1. Tooth movement relative to the alveolar bone can be precisely described only by superimposing on fixed points in the bone. Implants are the best known way today. Over short-term studies laminagraphy and the use of bony trabeculations are also useful. Remodeling occurs extensively on bony surfaces, making them too labile for use as stable landmarks. To project small amounts of tooth movement based on the use of such methods is so questionable as to represent little better than a guess or a clinical impression. 2. Growth can be separated into vertical and anteroposterior vectors with respect to the dentition. Since the occlusion is the concern, orientation of vertical and anteroposterior vectors to the occlusal plane is a reasonable baseline. The vertical and anteroposterior dental changes may not show a linear relationship in the anterior and posterior parts of the mouth when jaw rotations are occurring. 3. Growth can be disproportionate in either the vertical and/or the anteroposteroir plane of space. If the vertical increments of the anterior face differ from the vertical increments at the posterior face, mandibular rotations occur. This growth is accompanied by dental compensations that tend to mask the rotation. Therefore, open bite and deep bite are frequently skeletal growth problems. 4. Disproportional forward growth of the maxilla or mandible in an anteroposterior direction can lead to Class II or III relations. The growth that leads to Class II or Class III is accompanied by dental migrations that tend to mask this disproportionate growth. Orthodontic treatment of growth disproportionalities usually represents attempts to make the teeth further compensate. If surgical options are elected, the dental compensations should be removed prior to surgery in order to achieve a full surgical correction. 5. The teeth tend to move and grow in the opposite direction of the growth disproportionality. The teeth tend to mask the disproportionality. Thus, in an open bite, the incisors tend to move vertically further than in deep bites. Vertical imbalances may be more difficult to mask. Backward rotation of the mandible requires more vertical movement at the incisor than at the molar just to maintain vertical incisor relationships.

Child↗