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Biomedical subjects

R J Erickson

Publications and source records attributed to R J Erickson.

23 records · Page 2Linked to original sources
PubMed1966

Differential effects of deoxyribonucleotides on respiration of virulent pneumococci.

Firshein, William (Wesleyan University, Middletown, Conn.), Robert J. Erickson, and Bernadette A. Gargan. Differential effects of deoxyribonucleotides on respiration of virulent pneumococci. J. Bacteriol. 92:1645-1654. 1966.-Four naturally occurring deoxyribonucleotides affect respiration in three virulent pneumococcal types (Diplococcus pneumoniae) differentially. Deoxyadenylic acid (dAMP) stimulates respiration in type I and slightly stimulates respiration in type III, but has no effect in type II. Deoxyguanylic acid (dGMP) stimulates respiration in type I, inhibits respiration in type II, and has no effect in type III. Thymidylic acid (dTMP) inhibits respiration of type I, but is stimulatory in types II and III. Deoxycytidylic acid (dCMP) inhibits respiration of all three pneumococcal types. Of a large number of related compounds, including many of the naturally occurring deoxynucleosides, nucleosides, nucleotides, purines, and pyrimidines, thymidine is slightly effective in types II and III, and deoxycytidine is slightly inhibitory in all three types. None of the remaining compounds affects respiration significantly. With a few exceptions, there is a correlation between the extent of uptake of each deoxynucleotide in the three types and their ability to stimulate (or inhibit) respiration. The greater the uptake, the greater the enhancement of respiration. The less uptake, the greater the inhibition of respiration. In cell-free extracts of type I, dAMP also stimulates the oxidative decarboxylation of pyruvic acid. During this reaction, dAMP is phosphorylated to deoxyadenosine diphosphate (dADP) and to deoxyadenosine triphosphate (dATP).

Carbon Isotopes↗
PubMedDate not supplied

Retail employees as a group at risk for violence.

Citing studies in which convicted robbers have been interviewed to determine their motives and what factors may have deterred them from committing a planned robbery, the author traces patterns of violence at convenience stores over the past 20 years. She points out that because two thirds of workplace homicides are robbery-related, any efforts to stem the number of robberies will probably also curb the number of homicides.

Accidents, Occupational↗