Search PubMed⌕ Search

Biomedical subjects

R J Eltringham

Publications and source records attributed to R J Eltringham.

At least 37 records · Page 2Linked to original sources
PubMed1985

Anaesthetic management of the morbidly obese.

The problems associated with obesity are brought into sharp focus at the time of a surgical operation. The anaesthetist has a major role to play in preventing serious complications and must be aware of the many potential hazards. Extra vigilance is required to guide these patients safely through the perioperative period.

Adult↗
PubMed1983

Ethamsylate in vaginal surgery under lumbar epidural anaesthesia.

Sixty patients scheduled for vaginal surgery under lumbar epidural block were randomly allocated into two groups, one of which received ethamsylate intravenously prior to induction of anaesthesia. Ethamsylate did not reduce the blood loss at operation in these patients. The possible factors underlying this observation are discussed.

Adult↗
PubMed1982

Hypotensive anaesthesia for microsurgery of the middle ear. A comparison between enflurane and halothane.

One hundred patients undergoing microsurgery of the ear were anaesthetised using thiopentone, nitrous oxide, oxygen and either halothane or enflurane with spontaneous respiration. Blood pressure was reduced to approximately 70 mmHg by the use of hypotensive agents. The efficacy of halothane and enflurane in producing good operating conditions was compared during this technique. Haemostasis was assessed by the surgeon who was unaware which volatile agent was being used. Both agents were found to be satisfactory and enflurane was shown to be a safe and reliable agent with this technique should an alternative to halothane be required. No impairment of renal function was seen with either agent in combination with hypotension.

Adolescent↗
PubMed1981

Temazepam as premedication in day surgery.

Sixty patients scheduled for day case surgery were allocated into two groups in a double-blind study. One group received temazepam 20 mg or 30 mg orally 1 hour before surgery whilst the second group received a placebo of identical appearance. The use of temazepam was followed by a greater frequency of sedation and anxiolysis and with fewer problems at induction. The time to awaken, the level of postoperative sedation and the ability to walk unaided were similar in both groups. Postoperative sequelae were less frequent in the temazepam group. Temazepam is advocated as a suitable drug for premedication in day case surgery.

Adolescent↗
PubMed1981

Lorazepam in intensive care.

The suitability of lorazepam as a sedative for use in intensive care has been critically evaluated in 36 severely ill patients. The efficacy of lorazepam has been evaluated by regular measurements of both cardiovascular and neurological status as well as by the nursing staff directly involved with the care of the patients. A variety of patients have received lorazepam for sedation both while on intermittent positive pressure ventilation and when breathing spontaneously. The benefits of the predictable and even sedation produced by a long-acting drug of this nature are discussed. Particular attention has been paid to the possibility of accumulation of lorazepam in a similar way to that of diazepam, and the relative advantages of the two drugs for use in the intensive care situation have been compared.

Adolescent↗
PubMed1980

Lorazepam as night sedation and premedication: a comparison with diazepam.

Fifty healthy female patients scheduled for surgery were randonly allocated into two groups in a double-blind study. One group received lorazepam 2.5 mg orally at 2200 h on the evening before surgery as night sedation, and again at 0800 h on the morning before surgery as premedication. The second group received diazepam 10 mg orally at the samte times. The quality of sleep the night before surgery was superior in the lorazepam group (p less than 0.02). The frequency of effective sedation produced pre-operatively was similar in both groups. Although the incidence of amnesia for visual stimuli following lorazapam was higher (p less than 0.05) than with diazepam, there was no difference in the recall of auditory and painful stimuli. The overall incidence of side effects was similar for each drug and at the dosage used no difference was found in the time to awaken from anaesthesia.

Adult↗
PubMed1979

The effect of thiopentone and fazadinium on intraocular pressure.

Intraocular pressure was measured in twenty-four patients using an applanation tonometer, after using thiopentone and fazadinium as induction agents. No significant rise in intraocular pressure above resting levels was noted before or after tracheal intubation, and it is suggested that this combination of induction agents should be satisfactory for general anaesthesia of a patient with a perforating eye injury who presents with a full stomach.

Adolescent↗
PubMed1978

Observations on 10,000 patients in the immediate postoperative period.

During an 18 month period 10,103 patients were admitted to the recovery unit after surgery at a district general hospital. The majority of patients (62%) recovered rapidly from anaesthesia, but 36.5% required up to 2 h before they could return to the wards, and 1.5% required close supervision for more than 2 h. The patients' requirements during the recovery period are discussed, and suggestions on the equipment, staffing and organization of a recovery unit are made.

Aminophylline↗
PubMed1977

Possible dangers of anaesthesia in patients receiving fenfluramine. Results of animal studies following a case of human cardiac arrest.

Following the report of the death of a patient concurrently taking fenfluramine, following routine general anaesthesia, a series of anaesthetised rabbits received injections of adrenaline or fenfluramine. There were abnormal electrocardiographic changes and phonocardiographic evidence of altered heart activity in both groups, but the changes seen with fenfluramine were greater in number and less readily reversed with beta blockers and resuscitative drugs. This evidence may support an interaction between halothane and fenfluramine in man, and it is suggested that the latter drug be discontinued for a week prior to anaesthesia for elective surgery.

Adult↗