Search PubMed⌕ Search

Biomedical subjects

R J Earlam

Publications and source records attributed to R J Earlam.

At least 37 records · Page 2Linked to original sources
PubMed1983

General surgical workload in England and Wales.

An attempt was made to measure the workload of a typical general surgical firm (two part time consultants and their junior staff) serving a population of 100 000 in England and Wales. This provides a background against which to plan curricula for undergraduate and postgraduate teaching, as well as being a guide to the experience that a surgical trainee should get in a suitable training post. The effect of changes in surgical staffing on the number of operations done by a surgeon may also be estimated.

Bed Occupancy↗
PubMed1978

The clinical significance of gallstones and their radiological investigation.

The symptoms of 122 patients with gallstones were correlated with the radiological findings. No specific indigestion was present which could be termed 'flatulent dyspepsia'. Sensitivity to fatty foods occurred in 69 per cent, heartburn in 42 per cent, regurgitation of of acidtasting or bitter fluid to the mouth in 31 per cent and increased passage of flatus from the stomach upwards in 38 per cent. If the gallbladder concentrated contrast medium or an oral cholecystogram but did not contract after a fatty meal, the patients suffered less heartburn than if the gall bladder functioned normally. However, since surgeons rarely perform a cholecystectomy for flatulent dyspepsia alone, knowlege of gallbladder function may be unnecessary.

Adult↗
PubMed1972

Further experience with epigastric pain reproduction test in duodenal ulceration.

Further evidence is presented that the epigastric pain of duodenal ulceration, situated between the rib margins and just below the xiphisternum, arises from the lower oesophagus.One-hundred patients with duodenal ulceration were divided into those with epigastric pain (61) and those with pain in the upper abdomen but not in the epigastrium (39). Perfusion of 0.1 N HCl into the lower oesophagus reproduced epigastric pain in 53 of the 61 with epigastric pain (mean 37 ml) but in none of the 39 without (mean 125 ml). All those who had been woken by epigastric pain at night in the previous four weeks had a positive test.In five the test remained positive even though the acid was neutralized by a continuous perfusion of alkali just below the gastro-oesophageal junction. In another five 200 ml 0.1 N HCl instilled into the stomach for 21 minutes did not reproduce epigastric pain, even though 30 ml perfused for three minutes into the lower oesophagus did.

Bicarbonates↗
PubMed1971

Ganglion cell changes in experimental stenosis of the gut.

Teflon mesh was wrapped around the terminal ileum of dogs to cause a partial obstruction. Both smooth muscle layers became thickened in the gut proximal to the constriction, but the circular muscle was more hypertrophied than the longitudinal. The cells in Auerbach's plexus were stained by an indoxyl esterate technique in 100mu sections and counted. The number of ganglion cells related to muscle mass was decreased above the constriction. Although some ganglion cells increased in size there was no evidence of any increase in number.

Animals↗
PubMed1970

Production of epigastric pain in duodenal ulcer by lower oesophageal acid perfusion.

Thirty-six patients with duodenal ulceration were divided into group 1 (30), who had epigastric pain, and group 2 (6), who had pain in the upper abdomen but not in the epigastrium, and were studied by perfusing the lower oesophagus with dilute acid in an attempt to reproduce epigastric pain. In group 1, 25 suffered epigastric pain, indistinguishable from that which they normally had, after perfusion of 30 ml. of 0.1N HC1 in under four minutes (mean values), but none of group 2 had pain.

Abdomen↗