Search PubMed⌕ Search

Biomedical subjects

R J Brummer

Publications and source records attributed to R J Brummer.

60 records · Page 4Linked to original sources
PubMed1985

The hydrogen (H2) breath test. Sampling methods and the influence of dietary fibre on fasting level.

Three end-expiratory breath hydrogen (H2) sampling methods were compared in a patient group (n = 12) and a laboratory staff group (n = 12) on two separate occasions. H2 samples obtained with each method showed significantly different concentrations (p less than 0.001) but no significant differences in coefficient of variation when individual triplicate samples were evaluated. There was a high correlation between the breath H2 concentrations obtained by the three methods (r = 0.93-0.96). Fasting breath H2 values after an overnight fast and an unrestricted diet the day before the investigation were compared with values obtained after an overnight fast and a low-fibre diet the day before the test in two patient groups (n = 39 and 39) with a comparable distribution of diagnoses and in one group of healthy volunteers (n = 17). Fasting breath H2 concentrations were significantly lower after a low-fibre diet in the patient groups (p less than 0.005) and in healthy volunteers (p less than 0.02). We conclude that each of the three end-expiratory sampling methods can be chosen for use in H2 breath tests depending on suitability and convenience and that a low-fibre diet the day before the H2 breath test lowers fasting breath H2 concentration.

Adult↗
PubMed1984

Effect of different starchy foods in composite meals on gastric emptying rate and glucose metabolism. I. Comparisons between potatoes, rice and white beans.

Thirteen healthy subjects participated in the study. Three meals of equal energy content consisting of hamburgers and mashed potatoes, polished rice or white beans were studied. The various meals were labelled with 2.6 MBq 51Cr and gastric emptying was studied by a movable NaI (T1) detector. Blood glucose and plasma insulin were measured after an overnight fast and after ingestion of the testmeal. Gastric emptying of mashed potatoes was faster than that of polished rice (P less than 0.02) and of white beans (P less than 0.05). Blood glucose and plasma insulin responses to the meal with mashed potatoes were greater than to that with polished rice (P less than 0.01), which also produced a greater glucose response than that with white beans (P less than 0.01). The correlation coefficient (rs) between difference in gastric emptying and difference in blood glucose or plasma insulin response was 0.95 (P less than 0.01) when comparing meals of mashed potatoes and polished rice. No correlation was found between gastric emptying and blood glucose or plasma insulin after the white bean meal. We conclude that glucose and insulin responses to potatoes and rice are strongly related to gastric emptying rate, but other factors dominate the control of these responses to white beans.

Adult↗