Retinoschisis. Complication of peripheral uveitis.
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Humans↗
Biomedical subjects
R J Brockhurst
Publications and source records attributed to R J Brockhurst.
Pathologic findings in familial exudative vitreoretinopathy.
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Adolescent↗
Central serous choroidopathy in the Hallermann-Streiff Syndrome.
Central serous choroidopathy was observed in a young patient with the Hallermann-Streiff syndrome. Typical features of this syndrome include microphthalmos, proportionate dwarfism, dyscephaly with birdlike facies, dental abnormalities, and hypotrichosis. Exceptional aspects of this case include age of onset (11 years), high hyperopic refractive error (+ 13.00 sphere), and multiple recurrences caused by six separate documented leaks from the choroid. Fundus changes previously reported in the Hallermann-Streiff syndrome, interpreted as chorioretinal pigmentary changes, may have been secondary to previous undiagnosed central serous choroidopathy. Periodic ophthalmoscopy should be performed and may detect unrecognized episodes of central serous choroidopathy for which photocoagulation would be beneficial.
Adolescent↗
Vortex vein decompression for nanophthalmic uveal effusion.
Uveal effusion in nanophthalmic eyes probably is the result of choroidal congestion secondary to imparied vortex venous drainage through the thick sclera that is characteristic of nanophthalmos. Ten eyes with nonrhegmatogenous retinal detachment, occurring in nanophthalmic eyes, were treated by vortex vein decompression and, in some cases, drainage of choroidal and/or subretinal fluid with air injection into the vitreous cavity. Eight of the ten eyes showed reattachment of the retina after this procedure. There results support the hypothesis that choroidal congestion is the basic mechanism of nanophthalmic uveal effusion.
Aged↗
Photocoagulation of active toxoplasmic retinochoroiditis.
Active, recurrent, protracted toxoplasmic retinochoroiditis that had been unresponsive to intensive medical therapy with pyrimethamine, sulfamethoxypyridazine, intramuscular folicic acid, or clindamycin and corticosteroids, was treated with photocoagulation in five eyes. Four eyes healed rapidly within a few weeks. In one patient's eye, lens and vitreous opacities prevented adequate treatment with the red III intensity level of the xenon are photocoagulator. Subsequent surgical diathermy and cryocoagulation resulted in prompt healing of the lesion. Noninvasive photocoagulation of active toxoplasmosis retinochoroiditis is recommended in protracted cases if the media are clear, the macula is threatened, or there are severe complications from systemic medications.
Adolescent↗
Tantalum buttons for localization of malignant melanoma in proton beam therapy.
A radio-opaque button is described for scleral marking of choroidal malignant melanomas for subsequent proton beam irradiation. Since only one polyester suture is necessary to secure the button, whereas two sutures are required for conventional rings, the risk of inadvertent perforation of the sclera is reduced by one-half.
Choroid Neoplasms↗
Retractor for retinal detachment surgery.
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Humans↗
Angle-closure glaucoma in nanophthalmos.
Two patients had nanophthalmos with uveal effusion and angle-closure glaucoma. They were treated with a method based on the use of the laser, not only to perform iridotomy but to shrink the iris stroma, which appears to open the anterior chamber angle even without iridotomy. Additionally, we introduced three factors that may be diagnostic of nanophthalmos.
Choroid↗
Angioma-like lesion in hemoglobin sickle cell disease.
A lesion resembling a retinal angioma is reported in a 52-year-old man with hemoglobin S-C disease. Following surgery to destroy the tumor, the patient died. Postmortem examination confirmed sickle cell disease and the ocular findings revealed an angioma on the anterior side of the retina. It is believed this is the first report of sickle cell disease showing a large retinal angioma.
Anemia, Sickle Cell↗
Uveal effusion following pan-retinal photocoagulation.
Uveal effusion combined with nonrhegmatogenous retinal detachment is presented as a complication of pan-retinal photocoagulation in diabetic patients. This complication is believed to be a direct effect of photocoagulation on the choroidal vasculature. The mechanism is postulated to be secondary to photocoagulation-induced choroiditis, choroidal vascular occlusion, or a combination of the two. Corticosteroid therapy is recommended as being effective in resolving the choroidal effusion.
Choroid↗
Proton irradiation of choroidal melanomas. Preliminary results.
Choroidal malignant melanomas in nine patients were treated with proton beam irradiation at the Harvard Cyclotron Laboratory, Cambridge, Mass. Each patient received five proton beam treatments in eight to ten days, totalling 4,730 to 8,570 rads at the tumor. No complications occurred during the treatment or follow-up period, which, at the time of this writing, ranges from one to 24 months, with an average of 12 months. No further growth of the tumor has been observed in any patient. Different signs of tumor regression have been noted. Resolution of the serous retinal detachments that accompanied some tumors is the earliest finding. Pigment changes over the surface of the tumor and adjacent pigment epithelium is a usual initial tumor response. Fluorescein angiography initially showed decreased leakage of dye; later, destruction of the tumor's vasculature and elimination of fluorescein leakage became evident. Only large choroidal vessels remained patient. Ultrasonography revealed decreased height of the tumors postirradiation, and the radioactive phosphorus (32P) uptake test, repeated in one patient, turned negative on postirradiation measurements.
Aged↗
Cellular blue nevus of the sclera.
An isolated cellular blue nevus of the sclera was discovered and removed during a retinal detachment operation. Such benign tumors may be misdiagnosed clinically as an extension of a melanoma of the choroid or histologically as melanoma.
Choroid Neoplasms↗
Hemorrhagic detachment of the peripheral retinal pigment epithelium.
Six patients had hemorrhagic detachment of the peripheral retinal pigment epithelium. Abnormal neovascular nets in older individuals, under the retinal pigment epithelium and originating from the choriocapillaris, may well be the cause of such hemorrhagic detachments. This lesion must be differentiated from choroidal tumors, choroidal detachment, and uveal effusion.
Adult↗
Perforating diathermy coagulation for retinal angiomas.
Perforating diathermy coagulation can be used efficiently to destroy large angiomas of the retina. Five patients who had developed large angiomas (greater than 5 disc diameters) in association with various retinal diseases were treated with this technique. The follow-up period ranged from 1 1/2 to 7 years, except for one case in which the patient died five days after the surgical procedure. Several techniques of perforating diathermy are described, and the indications, surgical precautions, and complications of each method are discussed.
Adolescent↗
Nanophthalmos with uveal effusion. A new clinical entity.
Five patients exhibited the association of nanophthalmos and uveal effusion, apparently on a familial basis. Glaucoma, occurring in the fourth to sixth decades of life, required surgical intervention that was followed by the development of secondary retinal and choroidal detachment. Recognition of this syndrome is important because: (1) surgical procedures for glaucoma should be avoided, if possible, in order to prevent the development of uveal effusion; (2) retinal detachment surgical procedures are ineffective in uveal effusion and should be avoided, and (3) choroidal elevation occurring in the uveal effusion phase may be erroneously diagnosed as an intraocular tumor and unnecessary enucleation may follow.
Adult↗
Cicatricial retrolental fibroplasia: its occurrence without oxygen administration and in full term infants.
Six patients demonstrating typical signs of the cicatricial phase of retrolental fibroplasia are presented. None of the patients had received supplemental oxygen treatment after birth, and three patients were full term with birth weights ever 6 1/2 pounds. Two of the three premature patients had been born prior to 1901, before the advent of oxygen therapy for premature infants. It is apparent from these observations that retrolental fibroplasia does occur without oxygen administration and also in full term infants.
Adolescent↗