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Biomedical subjects

R J Bird

Publications and source records attributed to R J Bird.

12 recordsLinked to original sources
PubMed1989

Predicting the blood pressure response to atenolol.

The fall in blood pressure in response to atenolol 50 mg per day has been estimated using ambulatory BP and heart rate monitoring during the day in 35 mild to moderate hypertensive patients. The fall in pressure for the group averaged 18.2 +/- 11.3/11.5 +/- 8.3 mmHg. The 95% confidence internals were 14.5-22.0 mmHg systolic and 8.8-14.3 mmHg diastolic with the individual responses in diastolic pressure being related to the pretreatment variability of diastolic pressure (r = 0.65 P less than 0.001) and to the initial heart rate (r = 0.35 P less than 0.05). With atenolol treatment the BP fall is greater in patients with a more unstable BP. Blood pressure reduction is achieved by reducing the level of cardiac activity.

Adult↗
PubMed1988

Green beliefs.

Explore the source record for details and available documents.

Biotechnology↗
PubMed1987

Partial vs total esophagectomy for advanced carcinoma of the hypopharynx.

Cancer of the hypopharynx is an aggressive disease with a poor prognosis irrespective of the therapeutic regimen instituted. Controversy centers around the extent of surgery required to adequately ablate the advanced cancers, particularly related to the role of esophagectomy. A literature review and analysis of 43 cases of advanced hypopharyngeal cancer treated with total laryngopharyngectomy and partial esophagectomy support the argument that in carefully selected situations, a partial esophagectomy is oncologically an adequate operation.

Aged↗
PubMed1980

Nape of neck flap.

Great advances in the field of reconstructive head and neck surgery have been made in the last 20 years, and although the nape of neck flap has not been used as frequently as the deltopectoral flap or the forehead flap, its contribution in this field has been significant. This paper discusses the flap's history, anatomical basis, and clinical applications. Advantages, disadvantages, and complications are discussed and the flap's role in modern head and neck reconstructive surgery is examined.

Adult↗
PubMed1980

Longterm effects of heavy irradiation to the neck.

The longterm effects of heavy irradiation to the neck are now well known. The literature contains reports of major skin contractures, hypothyroidism, laryngeal and tracheal stenosis, major vessel stenosis, and hypoplastic development of cervical vertebrae, but very rarely are all these complications seen in a single patient. Two patients have undergone extensive treatment at the Toronto General Hospital during the past decade for complications of neck irradiation in childhood and their stories should serve as yet another reminder that irradiation, although a major ally in oncological therapy when carefully applied, can be a tool of great destruction when used in excess.

Adult↗
PubMed1980

Fibromatosis presenting as vocal cord palsy.

For many years, pathologists have sought to create some order in the classification of non-metastasizing fibrous tissue disorders ranging from the benign keloid at one end of the scale to the "non-metastasizing fibrosarcoma" at the other. It is now generally accepted that these fibrous anomalies are members of the same family and the entire range from the most benign to the most bizarre is encompassed by the term "fibromatosis". Unfortunately, some of these lesions behave in a most aggressive manner and there appears to be little correlation between the histological appearance of the tumor and its clinical aggression. Some, particularly if occurring in the head and neck may pursue a relentless course and, defying all forms of therapy, result in death of the patient. Recently a young man presented with fibromatosis in the supraclavicular region. Despite a short history, the lesion was quite advanced and was considered surgically unresectable. Radiotherapy was thus considered to be the treatment of choice.

Adult↗
PubMed1980

Computerized tomography in head and neck tumor diagnosis.

Computerized tomography has revolutionized the investigation of head and neck tumors and so rapid are the advances in this field, reviews are often outdated at time of publication. Several cases are presented to demonstrate the value of computerized tomography in investigation of lesions involving the paranasal sinuses, nasopharynx, and soft tissues of the neck.

Adolescent↗
PubMed1979

Multiple tumors of the parotid gland.

Multiple tumors in a single major salivary gland are rare. Recently a patient with an acinic cell carcinoma and a Warthin's tumor in the same parotid gland was surgically treated at the Toronto General Hospital. A review of the world literature failed to reveal any report of this combination of tumors in the same gland.

Adenolymphoma↗
PubMedDate not supplied

Complications associated with free jejunal graft reconstruction of the pharyngoesophagus--a multiinstitutional experience with 52 cases.

Fifty-two patients who underwent reconstruction of the pharynx and esophagus using the free jejunal graft were retrospectively reviewed. The complications were categorized into those associated with the resection, those associated with the harvesting of the graft, and those related to the reconstruction per se. In this series, the graft failure rate was 7.6% with an overall success rate of 90.3%. Graft necrosis was found to be the most serious complication occurring in four patients. Methods of detection of graft necrosis and management of these complications are discussed.

Adolescent↗