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Biomedical subjects

R J Bennett

Publications and source records attributed to R J Bennett.

36 records · Page 2Linked to original sources

Ascorbic acid absorption in Crohn's disease. Studies using L-[carboxyl-14C]ascorbic acid.

Total body pool and intestinal absorption of ascorbic acid were studied in 12 patients undergoing operation for Crohn's disease (six with fistulae and six without) and in six control patients undergoing operation for reasons other than Crohn's disease. L-[carboxyl-14C]Ascorbic acid, 0.19-0.40 megabecquerels (MBq), was given orally. After a period of equilibration, the labeled ascorbic acid was flushed out of the patient's body tissues using large doses of unlabeled ascorbic acid. Intestinal absorption of ascorbic acid, assessed from the total cumulative urinary 14C recovery, was found to be similar in patients with fistulizing Crohn's disease (73.9 +/- 8.45%), those without fistulas (72.8 +/- 11.53%), and in controls (80.3 +/- 8.11%). Total body pools of ascorbic acid, calculated using the plasma 14C decay curves, were similar in patients with Crohn's disease with fistulas (17.1 +/- 5.91 mg/kg), patients without fistulas (9.6 +/- 3.58 mg/kg), and in controls (13.3 +/- 4.28 mg/kg). The results indicate that ascorbic acid absorption is normal in patients with both fistulizing and nonfistulizing Crohn's disease. The results suggest that routine supplements of vitamin C are not necessary unless oral ascorbic acid intake is low.

Adult↗

Demographic and budgetary influence on the geography of the poll tax: alarm or false alarm?

"The paper examines the influence of demographic change and the adaptation of local authority budgets on the level of poll tax between local authorities. The changes introduced by the Local Government Finance Act [in the United Kingdom] are argued to make almost all the possible variation between areas depend upon demography and local decisions on expenditure. Means of assessing local expenditure need are outlined and a consistent measure is developed which is used to estimate the relative contributions of changing need, tax base, new expenditures and grants over the period 1974-85 and up to 1991. 'New realism' in local authority spending is argued to combine with demographic change to allow radically reduced potential poll tax levies to be estimated than have been forecast by other sources. The reductions are particularly significant in inner London and many metropolitan districts."

Demography↗

Statistical analysis of spatial data in the presence of missing observations: a methodological guide and an application to urban census data.

"In this paper a simple introduction and guide to a widely applicable method for estimating missing data in fields of enquiry such as census maps or LANDSAT images are presented. The method given is a maximum likelihood procedure.... The algorithm is presented in the form of a simple tutorial guide. An example, of median income levels in Houston [Texas], is worked through in detail for missing cells in census data. The example is characterised by a variable mean and a general variance-covariance matrix."

Americas↗

DICOR surface treatments for enhanced bonding.

Treatments for preparing castable ceramic surfaces for enhanced bonding to specially formulated resin-based cements were examined. An ammonium bifluoride etch combined with gamma-methacryloxypropyl-trimethoxysilane produced shear bond strengths higher than when an ammonium bifluoride treatment was used alone. The method of curing the silane was highly significant in the contribution to the cement/substrate bond strength, with the heat-cure producing the highest values. Long-term water storage tests indicated that the cement bond with etch plus silane-treated castable ceramic surfaces (whether heat or chemically cured silane was used) demonstrated no significant decrease in strength after a one-year period.

Acid Etching, Dental↗

The operation of tympanomastoid re-aeration. Physiological repair of the radical mastoid cavity.

The aural cholesteatoma presents the triple problem of danger, discharge and deafness-a problem for many years answered by the classical radical surgery of the last century. The dissatisfaction with this approach has, however, been reflected in the various modifications that have recently culminated in the canal-conserving operation of the past decade or so. Gradually there has been a realization that the inherent, trouble-free stability of the normal healthy ear must be re-created before tympano-plastic repair of the hearing mechanism can be satisfactorily and indeed safely undertaken. This property of stability--the ability of the ear to "look after itself"--is dependent upon a natural environment for the constituent tissues that make up the sound conduction mechanism. Rational tympanoplastic surgery for aural cholesteatoma demands, therefore, both thorough disease excision and physiological reconstruction. This paper describes the priniciples and results of such a technique that I have used over the past ten years with increasing frequency. It combines the disease-excisive efficiency of the radical mastoid operation with a physiological rebuilding of the delicately balanced functional systems of the peripheral hearing mechanism.

Cholesteatoma↗

Perihepatic abscess detection on cholescintigraphy.

A case report of a 77-year-old woman with gallbladder perforation is presented. Perihepatic abscess formation was detected on radionuclide cholescintigraphy and abdominal ultrasonography. A perihepatic "halo" with nonvisualization of the gallbladder on radionuclide cholescintigraphy should suggest the diagnosis preoperatively.

Abscess↗

Study of autogenous transposed ossicles, bone and cartilage in man.

Study was made of 28 ossicles from 22 ears with chronic otitis, 12 autogenous transposed ossicles removed after varying periods of time, normal and 4 transplanted pieces of bone, and normal and 2 transplanted pieces of cartilage. The transposed ossicles were found to be dead, apart from certain special instances, showing pathology similar to non-transposed ossicles. Transplanted bone was also dead. Cartilage was vital. These autogenous transplants showed no evidence of rejection and less chronic inflammation than would be anticipated. It is suggested that autogenous ossicular or bone transplants in man act as inert but not rejected implants, while cartilage may remain viable.

Bone Transplantation↗