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Biomedical subjects

R Isaac

Publications and source records attributed to R Isaac.

35 records · Page 2Linked to original sources

Increased plasma calcitonin in early acute renal failure.

1. High plasma immunoreactive calcitonin concentrations were observed in ten of eleven patients with acute renal failure, particularly in the oliguric phase. 2. Immunoreactive calcitonin decreased progressively with time, independently of recovery of renal function. 3. Radioimmunoassay curves obtained with serial dilutions of plasma from these patients were parallel to or superimposed upon those obtained with calcitonin standards.

Acute Kidney Injury↗

Influence of calcium infusion on calcitonin and parathyroid hormone concentrations in normal and hemodialyzed subjects.

Plasma calcitonin and parathyroid hormone concentrations were compared before and after calcium infusion in both hemodialyzed patients and control subjects. Levels of both hormones were significantly higher in patients with chronic renal failure. In the uremic group, calcium infusion inhibited parathyroid hormone secretion but did not affect calcitonin. In the control group, calcium infusion stimulated calcitonin secretion but had no effect on parathyroid hormone.

Adult↗

Defining death.

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Death↗

Coroners act, 1972.

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Coroners and Medical Examiners↗

Impact of HIV infection/AIDS on social service agencies serving children and youth in Toronto.

There are few data on how HIV infection/AIDS affects social service agencies serving children and youth. We conducted a survey of 24 provincially funded agencies in the Metro Toronto area and discovered that 36 clients and 9 staff members were HIV-infected. Our data strongly suggest that these agencies were ill equipped to cope with issues surrounding HIV infection/AIDS. Inadequacy or absence of policy and procedures resulted in confusion regarding issues such as HIV testing, need to know, confidentiality, duty to warn, staff and client education, and universal precautions for infection control. In order to effectively deal with the psychosocial, legal, ethical and education needs of clients and staff, agencies must be pro-active in developing policy and procedure.

AIDS Serodiagnosis↗

[Hormonal stimulation after injection of thyrotrophin releasing factor (TRF) and 1-24 ACTH in patients following chronic treatment with neuroleptics (author's transl)].

Fifteen patients with neuroleptic treatment (haloperidol 4 to 6 mg a day or phenothiazines) and eleven control patients were given TRH 250 microgram i.v. and 1-24 ACTH, i.m. different times, TSH, T3, T4, FT4, Prolactin (PRL) cortisol were measured. Before TRH injection, at baseline, TSH is higher (p less than 0,01) and T3 lower (p less than 0,05) in the neuroleptics treated group than in the control group. These results suggest the occurrence of a biological hypothyroidism in the group with neuroleptics; moreover PRL is significantly increased. After TRH injection the response is not significantly different between the two groups. Cortisol level is lower at baseline and after 1-24 ACTH injections in the group with neuroleptics.

Adrenocorticotropic Hormone↗