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Biomedical subjects

R I Haddy

Publications and source records attributed to R I Haddy.

25 records · Page 2Linked to original sources

Antibiotic susceptibility of community hospital blood culture isolates of gram-negative bacilli.

The comparative in vitro activity of amikacin, cefamandole, cefoperazone, cefotaxime, cefoxitin, cephalothin, chloramphenicol, moxalactam, piperacillin, ticarcillin and tobramycin against 170 community blood culture isolates of gram-negative bacilli was investigated using the quantitative plate dilution method. Results showed that amikacin, cefoperazone, cefotaxime, moxalactam, piperacillin and tobramycin were most active on a weight basis. Tobramycin and amikacin were quite active against Pseudomonas aeruginosa but one isolate showed an MIC of 50 micrograms/ml to both. The order of activity of the remaining drugs for P. aeruginosa was cefoperazone greater than moxalactam greater than cefotaxime and piperacillin greater than ticarcillin.

Anti-Bacterial Agents↗

Munchausen's syndrome.

Munchausen's syndrome is a chronic condition in which patients with factitious illness present with dramatic and sometimes self-inflicted signs and symptoms. Much investigation is needed to delineate the etiology and psychodynamics of this disorder. After other causes for the patient's condition have been ruled out and a firm diagnosis is made, cautious confrontation with long-term psychotherapy, if the patient is amenable, is thought to be the best approach.

Adult↗

Bacterial endocarditis in the community hospital.

The clinical records of 66 patients with bacterial endocarditis hospitalized in three community hospitals in Saginaw, Michigan, from 1964 through 1979 were reviewed. Data from these nonreferral hospitals demonstrate that infective endocarditis often does not present to the primary care physician with classical physical findings. The etiological organisms were noted to change from being primarily alpha-hemolytic streptococci during the early part of the study to staphylococci and Streptococcus faecalis during later years. Narcotic addiction was a factor of increasing importance in the development of endocarditis and in the changing microbiology of this clinical syndrome.

Adolescent↗

Erythromycin resistance in group A beta-hemolytic streptococci.

Recent reports have indicated a high incidence of erythromycin resistance in Group A streptococci isolated from children in Japan. The present study investigated antibiotic susceptibility patterns of 280 pharyngeal isolates from ambulatory patients using the plate dilution technique. The incidences of resistance to erythromycin and tetracycline were 4.3 and 7.8%, respectively. No resistance to penicillin, ampicillin, methicillin, oxacillin, cefaclor or moxalactam was found, and there was no evidence of penicillin tolerance using the standard tube dilution technique. The erythromycin-resistant isolates were of T-pattern 12, M-type 12, and two erythromycin-resistant isolates were also resistant to tetracycline. Data on the source of the isolates suggest that a localized outbreak of erythromycin-resistant streptococcal infection occurred.

Anti-Bacterial Agents↗