The assay of orotate by an isotope dilution procedure.
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Carbon Radioisotopes↗
Biomedical subjects
R I Christopherson
Publications and source records attributed to R I Christopherson.
Regulation of aspartate carbamoyltransferase of Escherichia coli by the interrelationship of magnesium and nucleotides.
Purified aspartate carbamoyltransferase from Escherichia coli K12 (carbamoylphosphate: L-aspartate carbamyltransferase, EC 2.1.3.2) shows greater activity with nucleotide effectors as the magnesium nucleotide complex than with similar amounts of the sodium nucleotide. Regulation of aspartate carbamoyltransferase activity in vivo may occur by changes in the total concentration of regulatory nucleotides or, under conditions of magnesium-limited growth, by variation of the saturation of the nucleotides with magnesium.
Adenosine Triphosphate↗
A radioisotopic method for the assay of aspartate carbamoyltransferase and carbamoyl phosphate.
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Aspartate Carbamoyltransferase↗
Potent inhibitors of de novo pyrimidine and purine biosynthesis as chemotherapeutic agents.
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Animals↗