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Biomedical subjects

R Horton

Publications and source records attributed to R Horton.

At least 73 records · Page 4Linked to original sources
PubMed2000

War.

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Humans↗
PubMed2000

After Bezwoda.

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Antineoplastic Agents↗
PubMed1999

Transport and fate of volatile organic chemicals in unsaturated, nonisothermal, salty porous media: 1. Theoretical development.

A wide variety of volatile organic chemicals (VOC) have been applied to agricultural land or buried in chemical waste sites. The fate of these chemicals depends upon several mechanisms such as sorption, degradation, and transport in liquid and gaseous phases. Understanding the transport mechanisms affecting the volatile chemicals can lead to better management strategies. A theory describing inorganic solute transport, water and heat transfer, and the fate and transport of VOC in porous media has been developed. This theory includes matric water pressure head, solution osmotic pressure head, gravity pressure head, temperature, inorganic solute concentration, and VOC concentration gradients as driving forces for heat and mass transfer. The effect of surface tension, as a function of VOC concentration and temperature, on the matric water pressure head is included. The VOC can be associated with gas, liquid, and solid phases of the porous media. The gas and liquid phases are mobile, but the solid phase is immobile. The transfer of VOC across the gas/liquid, liquid/solid, and gas/solid interfaces is included using sorption-equilibrium assumptions at the interfaces. The VOC can degrade. This degradation is described by a first-order decay rate. The theory can be used to predict spatial and temporal variations of water content, temperature, inorganic concentration and the total concentration of VOC within a porous medium. The concentration of VOC in each phase can be predicted also.

Hot Temperature↗
PubMed1999

Transport and fate of volatile organic chemicals in unsaturated, nonisothermal, salty porous media: 2. Experimental and numerical studies for benzene.

Simultaneous transport in soil of heat, water, potassium chloride, and benzene was studied experimentally and numerically. A laboratory experiment permitted observation of temperature, water content, chloride concentration and benzene concentration distributions in soil. A numerical model based upon newly developed transport theory was used to simulate the observed data. Transport of benzene in soils was simulated numerically under isothermal and nonisothermal conditions. Simulated results for benzene were compared with experimental data. Experiments were conducted in sealed aluminum columns (0.05-m I.D. and 0.20-m length) with sterilized salinized unsaturated Fayette soil. The soil had initial water content of 0.22 m(3)/m(3) and initial inorganic solute concentration of 0.20 mol/kg. Benzene was injected at one end of each soil column (top end) to provide 143 g/m(3)gas. The results of this study indicated that transport models need to include the effect of temperature and temperature gradient to describe the movement of volatile chemicals in soils.

Benzene↗
PubMed1999

Gene organisation, sequence variation and isochore structure at the centromeric boundary of the human MHC.

We have mapped and sequenced the region immediately centromeric of the human major histocompatibility complex (MHC). A cluster of 13 genes/pseudogenes was identified in a 175 kb PAC linking the TAPASIN locus with the class II region. It includes two novel human genes (BING4 and SACM2L) and a thus far unnoticed human leucocyte antigen (HLA) class II pseudogene, termed HLA-DPA3. Analysis of the G+C content revealed an isochore boundary which, together with the previously reported telomeric boundary, defines the MHC class II region as one of the first completely sequenced isochores in the human genome. Comparison of the sequence with limited sequence from other cell lines shows that the high sequence variation found within the classical class II region extends beyond the identified isochore boundary leading us to propose the concept of an "extended MHC". By comparative analysis, we have precisely identified the mouse/human synteny breakpoint at the centromeric end of the extended MHC class II region between the genes HSET and PHF1.

Amino Acid Sequence↗